中国科学院南海海洋研究所机构知识库
Advanced  
SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室  > 期刊论文
学科主题: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
题名: Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production
作者: Zhang, SD ; Qin, JJ ; Jin, HZ ; Yin, YH ; Li, HL ; Yang, XW ; Li, X ; Shan, L ; Zhang, WD
通讯作者: shanleish@yahoo.com.cn ; wdzhangy@hotmail.com
关键词: Inula racemosa Hook. f. ; Compositae ; sesquiterpenes ; density functional theory ; nitric oxide
刊名: PLANTA MEDICA
发表日期: 2012-01-01
卷: 78, 期:2, 页:166-171
部门归属: [Yin, Yin-Hua; Li, Xia; Shan, Lei; Zhang, Wei-Dong] Mil Med Coll 2, Dept Nat Product Chem, Sch Pharm, Shanghai 200433, Peoples R China; [Zhang, Shou-De; Qin, Jiang-Jiang; Jin, Hui-Zi; Zhang, Wei-Dong] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China; [Li, Hong-Lin] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
项目归属: LMB
摘要: A novel trinorsesquiterpene (1), three new (2-4), and 10 known sesquiterpenes were isolated from the roots of Inula racemosa Hook. f. The structures and absolute configurations of the new sesquiterpenes were elucidated by extensive spectroscopic and computational methods. All compounds were evaluated for their inhibition of LPS-induced nitric oxide production in RAW264.7 macrophages, and the results indicated that compounds 9, 12, and 13 moderately inhibited nitric oxide production with IC50 values of 7.39 +/- 0.36, 6.35 +/- 0.26, and 5.39 +/- 0.18 mu M, respectively.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10014
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

Files in This Item:

There are no files associated with this item.


Recommended Citation:
Zhang, SD; Qin, JJ; Jin, HZ; Yin, YH; Li, HL; Yang, XW; Li, X; Shan, L; Zhang, WD.Sesquiterpenoids from Inula racemosa Hook. f. Inhibit Nitric Oxide Production,PLANTA MEDICA,2012,78(2):166-171
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhang, SD]'s Articles
[Qin, JJ]'s Articles
[Jin, HZ]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhang, SD]‘s Articles
[Qin, JJ]‘s Articles
[Jin, HZ]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院南海海洋研究所 - Feedback
Powered by CSpace