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学科主题: Chemistry, Organic
题名: A New Prenylated Flavanone from Derris trifoliata Lour
作者: Jiang, C ; Liu, SZ ; He, WH ; Luo, XM ; Zhang, S ; Xiao, ZH ; Qiu, XM ; Yin, H
通讯作者: dangdangli@tom.com ; shengziliu@163.com ; whhe@sisio.ac.cn ; luoxm163@sina.com ; zhsimd@scsio.ac.cn ; xzh_77@yahoo.com.cn ; qiuximin@tom.com ; yinhao@scsio.ac.cn
关键词: Derris trifoliate ; aerial part ; prenylated flavanone ; rotenoids ; brine shrimp toxicity
刊名: MOLECULES
发表日期: 2012-01-01
卷: 17, 期:1, 页:657-663
部门归属: [Jiang, Cheng; Liu, Shengzi; Qiu, Ximin] Hunan Normal Univ, Coll Med, Dept Pharm, Changsha 410006, Peoples R China; [He, Weihong; Luo, Xiongming; Zhang, Si; Xiao, Zhihui; Yin, Hao] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresourses Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
项目归属: LMB
摘要: A new flavanone, 4',5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)-flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy- 6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-methoxyflavanone. 7a-O-Methylelliptonol was isolated for the first time from the genus Derris. Their structures were characterized on the basis of spectral data. Eight of the isolated compounds were found to be significantly toxic to brine shrimp (LC50 range 0.06-9.95 mu g/mL). The new compound showed weak toxicity (LC50 = 211.31 mu g/mL).
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10018
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Jiang, C; Liu, SZ; He, WH; Luo, XM; Zhang, S; Xiao, ZH; Qiu, XM; Yin, H.A New Prenylated Flavanone from Derris trifoliata Lour,MOLECULES,2012,17(1):657-663
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文件名: A New Prenylated Flavanone from Derris trifoliata Lour.pdf
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