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A New Prenylated Flavanone from Derris trifoliata Lour
Jiang, C; Liu, SZ; He, WH; Luo, XM; Zhang, S; Xiao, ZH; Qiu, XM; Yin, H;;;;;;;;
Source PublicationMOLECULES
AbstractA new flavanone, 4',5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)-flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy- 6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-methoxyflavanone. 7a-O-Methylelliptonol was isolated for the first time from the genus Derris. Their structures were characterized on the basis of spectral data. Eight of the isolated compounds were found to be significantly toxic to brine shrimp (LC50 range 0.06-9.95 mu g/mL). The new compound showed weak toxicity (LC50 = 211.31 mu g/mL).
Department[Jiang, Cheng; Liu, Shengzi; Qiu, Ximin] Hunan Normal Univ, Coll Med, Dept Pharm, Changsha 410006, Peoples R China; [He, Weihong; Luo, Xiongming; Zhang, Si; Xiao, Zhihui; Yin, Hao] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresourses Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
KeywordDerris Trifoliate Aerial Part Prenylated Flavanone Rotenoids Brine Shrimp Toxicity
Subject AreaChemistry, Organic
Funding ProjectLMB
Document Type期刊论文
Recommended Citation
GB/T 7714
Jiang, C,Liu, SZ,He, WH,et al. A New Prenylated Flavanone from Derris trifoliata Lour[J]. MOLECULES,2012,17(1):657-663.
APA Jiang, C.,Liu, SZ.,He, WH.,Luo, XM.,Zhang, S.,...& New Prenylated Flavanone from Derris trifoliata Lour.MOLECULES,17(1),657-663.
MLA Jiang, C,et al."A New Prenylated Flavanone from Derris trifoliata Lour".MOLECULES 17.1(2012):657-663.
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