Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032
Zhang, WJ; Ma, L; Li, SM; Liu, Z; Chen, YC; Zhang, HB; Zhang, GT; Zhang, QB; Tian, XP; Yuan, CS; Zhang, S; Zhang, WM; Zhang, CS; czhang2006@gmail.com
2014
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号77期号:8页码:1887-1892
摘要Five new bisindole alkaloids, indimicins A-E (1-5), bearing a unique 1',3'-dimethyl-2'-hydroindole moiety, were isolated from the marine-derived Streptomyces sp. SCSIO 03032, along with two new compounds, lynamicins F and G (6 and 7). Their planar structures were elucidated by detailed interpretation of their MS and NMR spectroscopic data, and the absolute configurations were determined by X-ray crystallographic analysis (for 1), comparison of CD spectra (for 2-4), and quantum chemical calculations (for 5). Indimicin B (2) exhibited moderate cytotoxic activity toward the MCF-7 cell line.
部门归属[Zhang, Wenjun ; Ma, Liang ; Li, Sumei ; Zhang, Haibo ; Zhang, Guangtao ; Zhang, Qingbo ; Tian, Xinpeng ; Yuan, Chengshan ; Zhang, Si ; Zhang, Changsheng] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangdong Key Lab Marine Mat Med,Collaborat Innov, Guangzhou 510301, Guangdong, Peoples R China ; [Liu, Zhong] Jinan Univ, Guangdong Key Lab Bioengn Med, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China ; [Chen, Yuchan ; Zhang, Weimin] Guangdong Inst Microbiol, Guangzhou 510070, Guangdong, Peoples R China
学科领域Plant Sciences ; Pharmacology & Pharmacy
资助者MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002]
URL查看原文
收录类别sci
资助项目LMB
资助者MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002] ; MOST [2010CB833805, 2012AA092104]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; NSFC [31125001, 41106143, 41206138, 31290233]; Administration of Ocean and Fisheries of Guangdong Province [GD2012-D01-002]
WOS记录号WOS:000340861800017
引用统计
被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/10411
专题中科院海洋生物资源可持续利用重点实验室
通讯作者czhang2006@gmail.com
推荐引用方式
GB/T 7714
Zhang, WJ,Ma, L,Li, SM,et al. Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(8):1887-1892.
APA Zhang, WJ.,Ma, L.,Li, SM.,Liu, Z.,Chen, YC.,...&czhang2006@gmail.com.(2014).Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032.JOURNAL OF NATURAL PRODUCTS,77(8),1887-1892.
MLA Zhang, WJ,et al."Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp SCSIO 03032".JOURNAL OF NATURAL PRODUCTS 77.8(2014):1887-1892.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。