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学科主题: Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
题名: Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum
作者: Sun, JF ; Lin, XP ; Zhou, XF ; Wan, JT ; Zhang, TY ; Yang, B ; Yang, XW ; Tu, ZC ; Liu, YH
通讯作者: tu_zhengchao@gibh.ac.cn ; yonghongliu@scsio.ac.cn
关键词: Aegiceras corniculatum ; anti-tuberculosis ; antiviral ; benzaldehyde ; cytotoxicity ; endophytic fungi ; Pestalotiopsis sp AcBC2
刊名: JOURNAL OF ANTIBIOTICS
发表日期: 2014
卷: 67, 期:6, 页:451-457
收录类别: sci
部门归属: [Sun, Jian-Fan ; Lin, Xiuping ; Zhou, Xue-Feng ; Yang, Bin ; Yang, Xian-Wen ; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, Guangzhou, Guangdong, Peoples R China ; [Sun, Jian-Fan] Jiangsu Univ, Sch Environm, Zhenjiang, Peoples R China ; [Wan, Junting ; Zhang, Tianyu ; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, State Key Lab Resp Dis, Guangzhou 510530, Guangdong, Peoples R China
项目归属: LMB
资助者: National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002]
摘要: Five alkenyl phenol and benzaldehyde derivatives, pestalols A-E (1-5), as well as seven known compounds (6-12), were isolated from endophytic fungus Pestalotiopsis sp. AcBC2 derived from the Chinese mangrove plant Aegiceras corniculatum. Their structures were determined by spectroscopic analyses. Compounds 2 and 3 showed cytotoxicity against a panel of 10 tumor cell lines. Compounds 1-5, 8, 9, 11, and 12 showed inhibitory activities against Influenza A virus subtype (H3N2) and Swine Flu (H1N1) viruses. Compound 2 also showed inhibitory activity against tuberculosis.
原文出处: 查看原文
WOS记录号: WOS:000338771900005
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10431
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Sun, JF; Lin, XP; Zhou, XF; Wan, JT; Zhang, TY; Yang, B; Yang, XW; Tu, ZC; Liu, YH.Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum,JOURNAL OF ANTIBIOTICS,2014,67(6):451-457
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