Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum
Sun, JF; Lin, XP; Zhou, XF; Wan, JT; Zhang, TY; Yang, B; Yang, XW; Tu, ZC; Liu, YH; tu_zhengchao@gibh.ac.cn; yonghongliu@scsio.ac.cn
2014
发表期刊JOURNAL OF ANTIBIOTICS
ISSN0021-8820
卷号67期号:6页码:451-457
摘要Five alkenyl phenol and benzaldehyde derivatives, pestalols A-E (1-5), as well as seven known compounds (6-12), were isolated from endophytic fungus Pestalotiopsis sp. AcBC2 derived from the Chinese mangrove plant Aegiceras corniculatum. Their structures were determined by spectroscopic analyses. Compounds 2 and 3 showed cytotoxicity against a panel of 10 tumor cell lines. Compounds 1-5, 8, 9, 11, and 12 showed inhibitory activities against Influenza A virus subtype (H3N2) and Swine Flu (H1N1) viruses. Compound 2 also showed inhibitory activity against tuberculosis.
部门归属[Sun, Jian-Fan ; Lin, Xiuping ; Zhou, Xue-Feng ; Yang, Bin ; Yang, Xian-Wen ; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, Guangzhou, Guangdong, Peoples R China ; [Sun, Jian-Fan] Jiangsu Univ, Sch Environm, Zhenjiang, Peoples R China ; [Wan, Junting ; Zhang, Tianyu ; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, State Key Lab Resp Dis, Guangzhou 510530, Guangdong, Peoples R China
关键词Aegiceras Corniculatum Anti-tuberculosis Antiviral Benzaldehyde Cytotoxicity Endophytic Fungi Pestalotiopsis Sp Acbc2
学科领域Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
资助者National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002]
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收录类别sci
资助项目LMB
资助者National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002] ; National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012 D01 001, GD2012 D01 002]
WOS记录号WOS:000338771900005
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/10431
专题中科院海洋生物资源可持续利用重点实验室
通讯作者tu_zhengchao@gibh.ac.cn; yonghongliu@scsio.ac.cn
推荐引用方式
GB/T 7714
Sun, JF,Lin, XP,Zhou, XF,et al. Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum[J]. JOURNAL OF ANTIBIOTICS,2014,67(6):451-457.
APA Sun, JF.,Lin, XP.,Zhou, XF.,Wan, JT.,Zhang, TY.,...&yonghongliu@scsio.ac.cn.(2014).Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum.JOURNAL OF ANTIBIOTICS,67(6),451-457.
MLA Sun, JF,et al."Pestalols A-E, new alkenyl phenol and benzaldehyde derivatives from endophytic fungus Pestalotiopsis sp AcBC2 isolated from the Chinese mangrove plant Aegiceras corniculatum".JOURNAL OF ANTIBIOTICS 67.6(2014):451-457.
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