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学科主题: Pharmacology & Pharmacy
题名: New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp SCSIO 05240
作者: Fredimoses, M ; Zhou, XF ; Lin, XP ; Tian, XP ; Ai, W ; Wang, JF ; Liao, SR ; Liu, J ; Yang, B ; Yang, XW ; Liu, YH
通讯作者: moses10c@gmail.com ; xfzhou@scsio.ac.cn ; xiupinglin@hotmail.com ; xinpengtian@scsio.ac.cn ; aiwen747@gmail.com ; Junfeng1982a@163.com ; ljrss@126.com ; ljuan2010@qq.com ; bingo525@163.com ; xwyang@scsio.ac.cn ; yonghongliu@scsio.ac.cn
关键词: prenylxanthone ; Emericella ; deep-sea ; fungus
刊名: MARINE DRUGS
发表日期: 2014
卷: 12, 期:6, 页:3190-3202
收录类别: sci
部门归属: [Fredimoses, Mangaladoss ; Zhou, Xuefeng ; Lin, Xiuping ; Tian, Xinpeng ; Ai, Wen ; Wang, Junfeng ; Liao, Shengrong ; Liu, Juan ; Yang, Bin ; Yang, Xianwen ; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, Guangzhou 510301, Guangdong, Peoples R China
项目归属: LMB
资助者: National High Technology Research and Development Program of China (863 Program) [2012AA092104]; National Key Basic Research Program of China (973)'s project [2010CB833800, 2011CB915503]; Postdoctoral Science Foundation of China [2012M511848]; National Natural Science Foundation of China [31270402, 21172230, 41376162, 21302198]; Innovative Development and Regional Demonstration Project of Guangdong Marine Economy [GD2012-D01-001]
摘要: Four new prenylxanthones, emerixanthones A-D (1-4), together with six known analogues (5-10), were isolated from the culture of the deep-sea sediment derived fungus Emericella sp. SCSIO 05240, which was identified on the basis of morphology and ITS sequence analysis. The newstructures were determined by NMR (H-1, C-13 NMR, HSQC, HMBC, and H-1-H-1 COSY), MS, CD, and optical rotation analysis. The absolute configuration of prenylxanthone skeleton was also confirmed by the X-ray crystallographic analysis. Compounds 1and 3 showed weak antibacterial activities, and 4 displayed mild antifungal activities against agricultural pathogens.
原文出处: 查看原文
WOS记录号: WOS:000338189200005
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10432
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Fredimoses, M; Zhou, XF; Lin, XP; Tian, XP; Ai, W; Wang, JF; Liao, SR; Liu, J; Yang, B; Yang, XW; Liu, YH.New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp SCSIO 05240,MARINE DRUGS,2014,12(6):3190-3202
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