Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167
Sun, YL; Zhang, XY; Zheng, ZH; Xu, XY; Qi, SH; shuhuaqi@scsio.ac.cn
2014
发表期刊NATURAL PRODUCT RESEARCH
ISSN1478-6419
卷号28期号:4页码:239-244
摘要Three new polyketides penicitrinol G (1), penicitrinol H (2) and 2,11-dihydroxy-1-methoxycarbonyl-9-carboxylxanthone (3) together with one known cathepsin B inhibitor chrysophanol (4) were isolated from a culture broth of marine-derived fungus Penicillium citrinum SCSGAF 0167. Their structures were determined by spectroscopic methods. Compound 4 exhibited inhibitory activity against cathepsin B with IC50 value of 1.7 mu M.
部门归属[Sun, Yu-Lin ; Zhang, Xiao-Yong ; Xu, Xin-Ya ; Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China ; [Sun, Yu-Lin] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China ; [Zheng, Zhi-Hui] North China Pharmaceutical Grp Corp, New Drug Res & Dev Ctr, Shijiazhuang 052260, Hebei, Peoples R China
关键词Penicillium Citrinum Polyketide Cathepsin b Inhibitor
学科领域Chemistry ; Pharmacology & Pharmacy
资助者973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009]
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收录类别sci
资助项目LMB
资助者973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009] ; 973 Program of China [2010CB833803]; 863 Program of China [2012AA092104]; National Marine Public Welfare Research Project of China [201305017]; National Natural Science Foundation of China [40931160435, 40976090]; Science and Technology Foundation of Guangdong Province [2010B030600009]
WOS记录号WOS:000333939500004
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/10470
专题中科院海洋生物资源可持续利用重点实验室
通讯作者shuhuaqi@scsio.ac.cn
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Sun, YL,Zhang, XY,Zheng, ZH,et al. Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167[J]. NATURAL PRODUCT RESEARCH,2014,28(4):239-244.
APA Sun, YL,Zhang, XY,Zheng, ZH,Xu, XY,Qi, SH,&shuhuaqi@scsio.ac.cn.(2014).Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167.NATURAL PRODUCT RESEARCH,28(4),239-244.
MLA Sun, YL,et al."Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167".NATURAL PRODUCT RESEARCH 28.4(2014):239-244.
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