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学科主题: Chemistry ; Pharmacology & Pharmacy
题名: A new naphthalene glycoside from the sponge-derived fungus Arthrinium sp ZSDS1-F3
作者: Wang, JF ; Xu, FQ ; Wang, Z ; Lu, X ; Wan, JT ; Yang, B ; Zhou, XF ; Zhang, TY ; Tu, ZC ; Liu, YH
通讯作者: yonghongliu@scsio.ac.cn
关键词: Arthrinium sp ; sponge ; secondary metabolite ; naphthalene glycoside
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2014
卷: 28, 期:14, 页:x
收录类别: sci
部门归属: [Wang, Jun-Feng ; Yang, Bin ; Zhou, Xue-Feng ; Liu, Yonghong] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, South China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China ; [Xu, Fu-Quan] Huaihai Inst Technol, Jiangsu Key Lab Marine Biotechnol, Lianyungang 222005, Peoples R China ; [Wang, Zhen ; Lu, Xin ; Wan, Jun-Ting ; Zhang, Tian-Yu ; Tu, Zheng-Chao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China
项目归属: LMB
资助者: National Key Basic Research Program of China (973)'s Project [2010CB833800, 2011CB915503]; Jiangsu Key Laboratory of Marine Biotechnology, Huaihai Institute of Technology [2013HS005]; Open Foundation of the Key Lab of Marine Bioactive Substance and Modern Analytical Technique, SOA [MBSMAT-2013-02]; National Natural Science Foundation of China [31270402, 21172230, 20902094, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012-D01-001, GD2012-D01-002]
摘要: One new naphthalene derivative, 1,8-dihydroxynaphthol-1-O--l-rhamnopyranoside (1), together with one known -dibenzopyrone, alternariol (2), and five xanthones (3-7) were isolated from the sponge-derived fungus Arthrinium sp. ZSDS1-F3. All the isolated compounds (1-7) were established by comprehensive analysis of the spectral data, especially 1D and 2D NMR (HMQC and HMBC) spectra. In the primary bioassays, compound 3 exhibited moderate COX-2 inhibition, with IC50 values of 12.2M.
原文出处: 查看原文
WOS记录号: WOS:000338988600007
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10484
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
Wang, JF; Xu, FQ; Wang, Z; Lu, X; Wan, JT; Yang, B; Zhou, XF; Zhang, TY; Tu, ZC; Liu, YH.A new naphthalene glycoside from the sponge-derived fungus Arthrinium sp ZSDS1-F3,NATURAL PRODUCT RESEARCH,2014,28(14):x
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