中国科学院南海海洋研究所机构知识库
Advanced  
SCSIO OpenIR  > 广东省海洋药物重点实验室  > 期刊论文
学科主题: Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
题名: Cytotoxic and antiviral nitrobenzoyl sesquiterpenoids from the marine-derived fungus Aspergillus ochraceus Jcma1F17
作者: Fang, W ; Lin, XP ; Zhou, XF ; Wan, JT ; Lu, X ; Yang, B ; Ai, W ; Lin, J ; Zhang, TY ; Tu, ZC ; Liu, YH
通讯作者: xfzhou@scsio.ac.cn ; yonghongliu@scsio.ac.cn
刊名: MEDCHEMCOMM
发表日期: 2014
卷: 5, 期:6, 页:701-705
收录类别: sci
部门归属: [Fang, Wei] Hubei Acad Agr Sci, Ctr Biopesticide Engn Res, Wuhan 430064, Peoples R China ; [Lin, Xiuping ; Zhou, Xuefeng ; Yang, Bin ; Ai, Wen ; Lin, Ji ; Liu, Yonghong] Chinese Acad Sci, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol, South China Sea Inst Oceanol,CAS Key Lab Trop Mar, Guangzhou 510301, Guangdong, Peoples R China
项目归属: 广东省海洋药物重点实验室
资助者: National Natural Science Foundation of China [41376162, 21302198, 31270402, 21172230]; National High Technology Research and Development Program of China [2012AA092104]; National Key Basic Research Program of China (973)'s project [2010CB833800, 2011CB915503]; Guangdong Natural Science Foundation [S2013010012474]; Innovative Development and Regional Demonstration Project of Guangdong Marine Economy [GD2012-D01-001]
摘要: Nitrobenzoyl sesquiterpenoids are rare in natural sources, and fungi Aspergillus species are the only sources of them. A new nitrobenzoyl sesquiterpenoid, 6 beta, 9 alpha-dihydroxy-14-p-nitrobenzoylcinnamolide (1), and a known analogue, insulicolide A (2), were isolated from extracts of the culture of marine-derived fungus Aspergillus ochraceus Jcma1F17, which was identified by morphological and ITS phylogenetic analyses. The structures were determined by NMR, MS, CD, and optical rotation analyses. Both nitrobenzoyl sesquiterpenoids displayed significant cytotoxicities against 10 cancer cell lines, and the new one (1) also showed antiviral activities against H3N2 and EV71. This is the first time that nitrobenzoyl sesquiterpenoids from A. ochraceus have been reported.
原文出处: 查看原文
WOS记录号: WOS:000336843000002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/10662
Appears in Collections:广东省海洋药物重点实验室_期刊论文

Files in This Item:

There are no files associated with this item.


Recommended Citation:
Fang, W; Lin, XP; Zhou, XF; Wan, JT; Lu, X; Yang, B; Ai, W; Lin, J; Zhang, TY; Tu, ZC; Liu, YH.Cytotoxic and antiviral nitrobenzoyl sesquiterpenoids from the marine-derived fungus Aspergillus ochraceus Jcma1F17,MEDCHEMCOMM,2014,5(6):701-705
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Fang, W]'s Articles
[Lin, XP]'s Articles
[Zhou, XF]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Fang, W]‘s Articles
[Lin, XP]‘s Articles
[Zhou, XF]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院南海海洋研究所 - Feedback
Powered by CSpace