Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355
[Yang, Xian-Wen; Peng, Kun; Zhang, Gai-Yun; Li, Jie; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China; Wang, Ning; Steinmetz, Andre] Luxembourg Publ Res Ctr Hlth CRP SANTE, L-1526 Luxembourg, Luxembourg; [Liu, Zhong] Jinan Univ, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China; ning.wang@crp-sante.lu; yonghongliu@scsio.ac.cn
2013
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:12页码:2360-2363
摘要Strepsesquitriol, a new caged sesquiterpene, was isolated from Streptomyces sp. SCSIO 10355. Its absolute structure was established as (1R,2R,4S,5S,8S,10S)-4,9,9,10-tetramethyl-2,5,10-trihydroxytricyclo[6.2.1.0(1,5)]undecane by NMR analysis and a theoretical optical rotation derived from quantum-chemical calculations. It showed moderate inhibitory activity against lipopolysaccharide-induced TNF alpha production in RAW264.7 macrophages.
部门归属LMB
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
资助者This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232).
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语种英语
资助者This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232).
WOS记录号WOS:000329331200026
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/10954
专题中科院海洋生物资源可持续利用重点实验室
通讯作者ning.wang@crp-sante.lu; yonghongliu@scsio.ac.cn
推荐引用方式
GB/T 7714
[Yang, Xian-Wen,Peng, Kun,Zhang, Gai-Yun,et al. Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(12):2360-2363.
APA [Yang, Xian-Wen.,Peng, Kun.,Zhang, Gai-Yun.,Li, Jie.,Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China.,...&yonghongliu@scsio.ac.cn.(2013).Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355.JOURNAL OF NATURAL PRODUCTS,76(12),2360-2363.
MLA [Yang, Xian-Wen,et al."Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355".JOURNAL OF NATURAL PRODUCTS 76.12(2013):2360-2363.
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