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Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355
[Yang, Xian-Wen; Peng, Kun; Zhang, Gai-Yun; Li, Jie; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China; Wang, Ning; Steinmetz, Andre] Luxembourg Publ Res Ctr Hlth CRP SANTE, L-1526 Luxembourg, Luxembourg; [Liu, Zhong] Jinan Univ, Guangzhoujinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China; ning.wang@crp-sante.lu; yonghongliu@scsio.ac.cn
2013
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume76Issue:12Pages:2360-2363
AbstractStrepsesquitriol, a new caged sesquiterpene, was isolated from Streptomyces sp. SCSIO 10355. Its absolute structure was established as (1R,2R,4S,5S,8S,10S)-4,9,9,10-tetramethyl-2,5,10-trihydroxytricyclo[6.2.1.0(1,5)]undecane by NMR analysis and a theoretical optical rotation derived from quantum-chemical calculations. It showed moderate inhibitory activity against lipopolysaccharide-induced TNF alpha production in RAW264.7 macrophages.
DepartmentLMB
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
Funding OrganizationThis study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232).
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Language英语
Funding OrganizationThis study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232). ; This study was supported by grants from the National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Key Basic Research Program of China (2010CB833800, 2011CB915503), National Natural Science Foundation of China (41176148, 21002110, 21372233), and FP7-People-IRSES-2008 (TCMCANCER Project 230232).
WOS IDWOS:000329331200026
Citation statistics
Cited Times:29[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/10954
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorning.wang@crp-sante.lu; yonghongliu@scsio.ac.cn
Recommended Citation
GB/T 7714
[Yang, Xian-Wen,Peng, Kun,Zhang, Gai-Yun,et al. Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(12):2360-2363.
APA [Yang, Xian-Wen.,Peng, Kun.,Zhang, Gai-Yun.,Li, Jie.,Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China.,...&yonghongliu@scsio.ac.cn.(2013).Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355.JOURNAL OF NATURAL PRODUCTS,76(12),2360-2363.
MLA [Yang, Xian-Wen,et al."Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp SCSIO 10355".JOURNAL OF NATURAL PRODUCTS 76.12(2013):2360-2363.
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