Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.
[Zhao, Min; Zhao, Feng; Cheng, Shimiao; Xiang, Zheng; Dong, Jianyong; Huang, Kexin; Yan, Pengcheng] Wenzhou Med Univ, Sch Pharm, Wenzhou 325035, Zhejiang, Peoples R China; [Li, Xiubao] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; xzh007@126.com; yanpc@wzmc.edu.cn
2013
发表期刊CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
卷号61期号:12页码:1323-1328
摘要Four new 7,8-epoxycembranoids, namely (2S*,7S*,8S*,12R*,1Z,3E,10E)-7,8:2,16-diepoxycembra-1(15), 3,10-trien-12-ol (1), (2S*,7S*,8S*,11R*,1Z,3E)-7,8:2,16-diepoxycembra-1(15),3,12(20)-trien-11-ol (2), (4S*, 7S*,8S*,1Z,2E,11E)-16-acetoxy-7,8-epoxycembra-1(15),2,11-trien-4-ol (3), and (7S*,8S*,15S*,1E,3E,11E)-7,8-epoxycembra-1,3,11-trien-15,16-diol (4) were isolated from a Chinese soft coral Lobophytum sp., together with eleven known analogues 5-15. The structures of the new compounds were determined by extensive spectroscopic data analysis. All compounds were tested for the inhibitory effect on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages (PEM Phi).
部门归属LMB
关键词Soft Coral Lobophytum Nitric Oxide (No) Inhibition 7 8-epoxycembranoid
学科领域Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
资助者This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018).
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语种英语
资助者This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018). ; This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018).
WOS记录号WOS:000327573700016
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/10957
专题中科院海洋生物资源可持续利用重点实验室
通讯作者xzh007@126.com; yanpc@wzmc.edu.cn
推荐引用方式
GB/T 7714
[Zhao, Min,Zhao, Feng,Cheng, Shimiao,et al. Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2013,61(12):1323-1328.
APA [Zhao, Min.,Zhao, Feng.,Cheng, Shimiao.,Xiang, Zheng.,Dong, Jianyong.,...&yanpc@wzmc.edu.cn.(2013).Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp..CHEMICAL & PHARMACEUTICAL BULLETIN,61(12),1323-1328.
MLA [Zhao, Min,et al."Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.".CHEMICAL & PHARMACEUTICAL BULLETIN 61.12(2013):1323-1328.
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