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Antiproliferative activity of peels, pulps and seeds of 61 fruits
[Li, Fang; Li, Sha; Li, Hua-Bin; Deng, Gui-Fang; Ling, Wen-Hua; Wu, Shan] Sun Yat Sen Univ, Guangdong Prov Key Lab Food Nutr & Hlth, Dept Nutr, Sch Publ Hlth, Guangzhou 510080, Guangdong, Peoples R China; [Xu, Xiang-Rong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Chen, Feng] Peking Univ, Coll Engn, Inst Food & Bioresource Engn, Beijing 100871, Peoples R China; lihuabin@mail.sysu.edu.cn; xuxr2000@yahoo.com
2013
Source PublicationJOURNAL OF FUNCTIONAL FOODS
ISSN1756-4646
Volume5Issue:3Pages:1298-1309
AbstractFruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61 fruits on four cancer cell lines, A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells) were evaluated by MTT assay. The results revealed that different fruits and different parts of one fruit exhibited different antiproliferative capacities. Nine of the 162 samples from 61 fruits showed remarkable inhibitory effects toward the four cancer cell lines, and all decreased the viability of the cancer cell lines in a dose-dependent manner. The results suggested that some fruits (such as honey peach, salak, orange, and Peru ground cherry) may serve as potential dietary supplement for the prevention and treatment of cancer because of strong antiproliferative activities against the cancer cell lines. (C) 2013 Elsevier Ltd. All rights reserved.
DepartmentLMB
KeywordFruit Peel Pulp Seed Antiproliferative Activity Cancer
Subject AreaFood Science & Technology
Funding OrganizationThis research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University.
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Language英语
Funding OrganizationThis research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University. ; This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University.
WOS IDWOS:000322691600031
Citation statistics
Cited Times:47[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11011
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorlihuabin@mail.sysu.edu.cn; xuxr2000@yahoo.com
Recommended Citation
GB/T 7714
[Li, Fang,Li, Sha,Li, Hua-Bin,et al. Antiproliferative activity of peels, pulps and seeds of 61 fruits[J]. JOURNAL OF FUNCTIONAL FOODS,2013,5(3):1298-1309.
APA [Li, Fang.,Li, Sha.,Li, Hua-Bin.,Deng, Gui-Fang.,Ling, Wen-Hua.,...&xuxr2000@yahoo.com.(2013).Antiproliferative activity of peels, pulps and seeds of 61 fruits.JOURNAL OF FUNCTIONAL FOODS,5(3),1298-1309.
MLA [Li, Fang,et al."Antiproliferative activity of peels, pulps and seeds of 61 fruits".JOURNAL OF FUNCTIONAL FOODS 5.3(2013):1298-1309.
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