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学科主题: Food Science & Technology
题名: Antiproliferative activity of peels, pulps and seeds of 61 fruits
作者: [Li, Fang ; Li, Sha ; Li, Hua-Bin ; Deng, Gui-Fang ; Ling, Wen-Hua ; Wu, Shan] Sun Yat Sen Univ, Guangdong Prov Key Lab Food Nutr & Hlth, Dept Nutr, Sch Publ Hlth, Guangzhou 510080, Guangdong, Peoples R China ; [Xu, Xiang-Rong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China ; [Chen, Feng] Peking Univ, Coll Engn, Inst Food & Bioresource Engn, Beijing 100871, Peoples R China
通讯作者: lihuabin@mail.sysu.edu.cn ; xuxr2000@yahoo.com
关键词: Fruit ; Peel ; Pulp ; Seed ; Antiproliferative activity ; Cancer
刊名: JOURNAL OF FUNCTIONAL FOODS
发表日期: 2013
卷: 5, 期:3, 页:1298-1309
部门归属: LMB
资助者: This research was supported by the Hundred-Talents Scheme of Chinese Academy of Sciences, and the Hundred-Talents Scheme of Sun Yat-Sen University.
摘要: Fruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61 fruits on four cancer cell lines, A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells) were evaluated by MTT assay. The results revealed that different fruits and different parts of one fruit exhibited different antiproliferative capacities. Nine of the 162 samples from 61 fruits showed remarkable inhibitory effects toward the four cancer cell lines, and all decreased the viability of the cancer cell lines in a dose-dependent manner. The results suggested that some fruits (such as honey peach, salak, orange, and Peru ground cherry) may serve as potential dietary supplement for the prevention and treatment of cancer because of strong antiproliferative activities against the cancer cell lines. (C) 2013 Elsevier Ltd. All rights reserved.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000322691600031
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11011
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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[Li, Fang; Li, Sha; Li, Hua-Bin; Deng, Gui-Fang; Ling, Wen-Hua; Wu, Shan] Sun Yat Sen Univ, Guangdong Prov Key Lab Food Nutr & Hlth, Dept Nutr, Sch Publ Hlth, Guangzhou 510080, Guangdong, Peoples R China; [Xu, Xiang-Rong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Chen, Feng] Peking Univ, Coll Engn, Inst Food & Bioresource Engn, Beijing 100871, Peoples R China.Antiproliferative activity of peels, pulps and seeds of 61 fruits,JOURNAL OF FUNCTIONAL FOODS,2013,5(3):1298-1309
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