Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
[Cai Bingna; Pan Jianyu; Wan Peng; Sun Huili] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Wu Yuantao] Chinese Acad Sci, Bur Sci & Technol Resource & Environm, Beijing 100864, Peoples R China; Sun Huili] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; shl@scsio.ac.cn
2013
发表期刊CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN0254-4059
卷号31期号:4页码:813-820
摘要Oyster peptides were produced from Crassostrea hongkongensis and used as a new protein source for the preparation of an oyster peptide-based enteral nutrition formula (OPENF). Reserpineinduced malabsorption mice and cyclophosphamide-induced immunosuppression mice were used in this study. OPENF powder is light yellow green and has a protein-fat-carbohydrate ratio of 16:9:75 with good solubility in water. A pilot study investigating immune functional impacts of the OPENF on mice show that the OPENF enhanced spleen lymphocyte proliferation and the activity of natural killer (NK) cells in BALB/c mice. Furthermore, OPENF can improve intestinal absorption, increase food utilization ratio, and maintain the normal physiological function of mice. These results suggest that oyster peptides could serve as a new protein source for use in enteral nutrition formula, but more importantly, also indicate that OPENF has an immunostimulating effect in mice.
部门归属LMB
关键词Marine Protein Oyster Peptides Enteral Nutrition Formula Immunomodulation
学科领域Limnology ; Oceanography
资助者Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a))
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语种英语
资助者Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a)) ; Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology Promotion Special Program of Guangdong Province (No. A2009009-035(a))
WOS记录号WOS:000321629400012
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被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/11013
专题中科院海洋生物资源可持续利用重点实验室
通讯作者shl@scsio.ac.cn
推荐引用方式
GB/T 7714
[Cai Bingna,Pan Jianyu,Wan Peng,et al. Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2013,31(4):813-820.
APA [Cai Bingna.,Pan Jianyu.,Wan Peng.,Sun Huili] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.,[Wu Yuantao] Chinese Acad Sci, Bur Sci & Technol Resource & Environm, Beijing 100864, Peoples R China.,...&shl@scsio.ac.cn.(2013).Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(4),813-820.
MLA [Cai Bingna,et al."Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 31.4(2013):813-820.
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