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学科主题: Chemistry, Applied ; Chemistry, Medicinal
题名: New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea
作者: [Sun, Ling-Ling ; Shao, Chang-Lun ; Xing, Qian ; Wang, Chang-Yun] Ocean Univ China, Sch Med & Pharmaceut, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China ; [Hang, Hui] Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510000, Guangdong, Peoples R China ; [Guo, Zhi-Yong] China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443002, Peoples R China
通讯作者: changyun@ouc.edu.cn
关键词: Anthogorgia caerulea ; gorgonian coral ; polyhydroxylated steroids ; absolute configuration
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2013
卷: 27, 期:13, 页:1159-1166
部门归属: LMB
资助者: This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002).
摘要: One new polyhydroxylated steroid, caerulsteroid A (1), along with nine known analogues (2-10), was isolated from the gorgonian coral Anthogorgia caerulea collected from the South China Sea. The structure of the new compound was elucidated by 1-D and 2-D NMR, and mass spectrometry. The absolute configuration of 1 was assigned on the basis of the absolute configurations of the related congeners 2 and 3, which were determined by application of the modified Mosher's method. The isolated compounds were assayed for their cytotoxicity, antimicrobial activity and lethality towards brine shrimp Artemia salina.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000321814300003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11014
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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[Sun, Ling-Ling; Shao, Chang-Lun; Xing, Qian; Wang, Chang-Yun] Ocean Univ China, Sch Med & Pharmaceut, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China; [Hang, Hui] Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510000, Guangdong, Peoples R China; [Guo, Zhi-Yong] China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443002, Peoples R China.New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea,NATURAL PRODUCT RESEARCH,2013,27(13):1159-1166
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