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New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea
[Sun, Ling-Ling; Shao, Chang-Lun; Xing, Qian; Wang, Chang-Yun] Ocean Univ China, Sch Med & Pharmaceut, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China; [Hang, Hui] Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510000, Guangdong, Peoples R China; [Guo, Zhi-Yong] China Three Gorges Univ, Coll Chem & Life Sci, Yichang 443002, Peoples R China; changyun@ouc.edu.cn
2013
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
Volume27Issue:13Pages:1159-1166
AbstractOne new polyhydroxylated steroid, caerulsteroid A (1), along with nine known analogues (2-10), was isolated from the gorgonian coral Anthogorgia caerulea collected from the South China Sea. The structure of the new compound was elucidated by 1-D and 2-D NMR, and mass spectrometry. The absolute configuration of 1 was assigned on the basis of the absolute configurations of the related congeners 2 and 3, which were determined by application of the modified Mosher's method. The isolated compounds were assayed for their cytotoxicity, antimicrobial activity and lethality towards brine shrimp Artemia salina.
DepartmentLMB
KeywordAnthogorgia Caerulea Gorgonian Coral Polyhydroxylated Steroids Absolute Configuration
Subject AreaChemistry, Applied ; Chemistry, Medicinal
Funding OrganizationThis study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002).
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Language英语
Funding OrganizationThis study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002). ; This study was supported by the Key Programme of National Natural Science Foundation of China (no. 41130858), the National Natural Science Foundation of China (nos. 40976077; 30901879; 41176121; 81172977), the Natural Science Foundation of Shandong Province (nos. ZR2011DQ019; ZR2011HM085) and the Research Fund for the Doctoral Programme of Higher Education, Ministry of Education of China (no. 20090132110002).
WOS IDWOS:000321814300003
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11014
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorchangyun@ouc.edu.cn
Recommended Citation
GB/T 7714
[Sun, Ling-Ling,Shao, Chang-Lun,Xing, Qian,et al. New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea[J]. NATURAL PRODUCT RESEARCH,2013,27(13):1159-1166.
APA [Sun, Ling-Ling.,Shao, Chang-Lun.,Xing, Qian.,Wang, Chang-Yun] Ocean Univ China, Sch Med & Pharmaceut, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China.,[Hang, Hui] Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510000, Guangdong, Peoples R China.,...&changyun@ouc.edu.cn.(2013).New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea.NATURAL PRODUCT RESEARCH,27(13),1159-1166.
MLA [Sun, Ling-Ling,et al."New polyhydroxylated steroid from the South China Sea gorgonian Anthogorgia caerulea".NATURAL PRODUCT RESEARCH 27.13(2013):1159-1166.
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