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Polyketides from a Marine-Derived Fungus Xylariaceae sp.
[Nong, Xu-Hua; Zhang, Xiao-Yong; Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China; [Nong, Xu-Hua] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Zheng, Zhi-Hui; Lu, Xin-Hua] North China Pharmaceutical Grp Corp, New Drug Res & Dev Ctr, Shijiazhuang 052260, Hebei, Peoples R China; nongxuhua4883@163.com; z_zhihui2003@yahoo.com.cn; zhangxiaoyong@scsio.ac.cn; luxinhua@ncpcrd.com.cn; shuhuaqi@scsio.ac.cn
2013
Source PublicationMARINE DRUGS
ISSN1660-3397
Volume11Issue:5Pages:1718-1727
AbstractEighteen polyketides (1-18) including six citrinin derivatives, two phenol derivatives, one cyclopentenone, two naphthol derivatives, and seven tetralone derivatives were isolated from the culture broth of a marine-derived fungal strain Xylariaceae sp. SCSGAF0086. Five of these compounds (1, 2, 8, 9, and 10) were new, and their structures were determined by spectroscopic methods. Compounds 4, 6, 7, and 17 showed enzyme-inhibitory activities towards several tested enzymes, and 6 and 7 showed strong antifouling activity against Bugula neritina larvae settlement. This is the first time that the antifouling and enzyme-inhibitory activities of these compounds has been reported.
DepartmentLMB
KeywordXylariaceae Sp. Polyketide Enzyme-inhibitory Activity Antifouling Activity
Subject AreaChemistry, Medicinal
Funding OrganizationThe authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support.
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Language英语
Funding OrganizationThe authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. ; The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support.
WOS IDWOS:000319440300019
Citation statistics
Cited Times:23[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11027
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authornongxuhua4883@163.com; z_zhihui2003@yahoo.com.cn; zhangxiaoyong@scsio.ac.cn; luxinhua@ncpcrd.com.cn; shuhuaqi@scsio.ac.cn
Recommended Citation
GB/T 7714
[Nong, Xu-Hua,Zhang, Xiao-Yong,Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China,et al. Polyketides from a Marine-Derived Fungus Xylariaceae sp.[J]. MARINE DRUGS,2013,11(5):1718-1727.
APA [Nong, Xu-Hua.,Zhang, Xiao-Yong.,Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China.,[Nong, Xu-Hua] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.,[Zheng, Zhi-Hui.,...&shuhuaqi@scsio.ac.cn.(2013).Polyketides from a Marine-Derived Fungus Xylariaceae sp..MARINE DRUGS,11(5),1718-1727.
MLA [Nong, Xu-Hua,et al."Polyketides from a Marine-Derived Fungus Xylariaceae sp.".MARINE DRUGS 11.5(2013):1718-1727.
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