SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室
Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase
[Li, Sumei; Xiao, Ji; Zhu, Yiguang; Zhang, Guangtao; Yang, Chunfang; Zhang, Haibo; Ma, Liang; Zhang, Changsheng] Chinese Acad Sci, CAS Key Lab Marine Bioresources Sustainable Utili, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China; [Xiao, Ji] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; czhang2006@gmail.com
2013
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume15Issue:6Pages:1374-1377
AbstractThe Identification of a lobophorin biosynthetic gene cluster from the deep-sea derived Streptomyces sp. SCSIO 01127 reveals a paradigm of three glycosyltransferases (GTs) LobG1-LobG3 being responsible for appending four sugars. Characterization of five differentially glycosylated metabolites from three GT gene-inactivation mutants allowed the assignment of GT functions and the implication of LobG3 as an iterative GT to attach two digitoxoses.
DepartmentLMB
Subject AreaChemistry, Organic
Funding OrganizationThis work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data.
URL查看原文
Language英语
Funding OrganizationThis work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data. ; This work is supported in part by NSFC (31125001), CAS (KZCX2-YW-JC202, KSCX2-EW-G-12, 08SL111002), and MOST (2010CB833805 and 2012AA092104). We are grateful to the analytical facility at SCSIO for recording NMR data.
WOS IDWOS:000316520300056
Citation statistics
Cited Times:31[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11052
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorczhang2006@gmail.com
Recommended Citation
GB/T 7714
[Li, Sumei,Xiao, Ji,Zhu, Yiguang,et al. Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase[J]. ORGANIC LETTERS,2013,15(6):1374-1377.
APA [Li, Sumei.,Xiao, Ji.,Zhu, Yiguang.,Zhang, Guangtao.,Yang, Chunfang.,...&czhang2006@gmail.com.(2013).Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase.ORGANIC LETTERS,15(6),1374-1377.
MLA [Li, Sumei,et al."Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase".ORGANIC LETTERS 15.6(2013):1374-1377.
Files in This Item:
File Name/Size DocType Version Access License
Dissecting Glycosyla(840KB) 开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.