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学科主题: Food Science & Technology ; Toxicology
题名: New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093
作者: [Xu, Xinya ; He, Fei ; Zhang, Xiaoyong ; Bao, Jie ; Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China ; [Bao, Jie] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者: shuhuaqi@scsio.ac.cn
关键词: Marine-derived fungus ; Aspergillus sp. ; Mycotoxins ; Aspergillic acid group ; Ochratoxins ; Brine shrimp toxicity
刊名: FOOD AND CHEMICAL TOXICOLOGY
发表日期: 2013
卷: 53, 页:46-51
部门归属: LMB
资助者: The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support.
摘要: Nine mycotoxins including six aspergillic acid group toxins, aluminiumneoaspergillin (1), zirconiumneoaspergillin (2), aspergilliamide (3), ferrineoaspergillin (5), flavacol (6), neoaspergillic acid (7), and three ochratoxins, ochratoxin A n-butyl ester (4), ochratoxin A (8), ochratoxin A methyl ester (9), were isolated from the fermentation broth of marine gorgonian derived fungus Aspergillus sp. SCSGAF0093. Four of them (1-4) were new mycotoxins, and their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. The bio-toxicity of compounds 1-9 were determined by brine shrimp lethality bioassay with median lethal concentration (LC50) values of 2.59-205.67 mu M. This was the first report about zirconium complex obtained from nature and ochratoxins isolated from marine environment. (c) 2012 Elsevier Ltd. All rights reserved.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000322924700008
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11055
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
[Xu, Xinya; He, Fei; Zhang, Xiaoyong; Bao, Jie; Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Bao, Jie] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093,FOOD AND CHEMICAL TOXICOLOGY,2013,53():46-51
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