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New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093
[Xu, Xinya; He, Fei; Zhang, Xiaoyong; Bao, Jie; Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Bao, Jie] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; shuhuaqi@scsio.ac.cn
2013
Source PublicationFOOD AND CHEMICAL TOXICOLOGY
ISSN0278-6915
Volume53Pages:46-51
AbstractNine mycotoxins including six aspergillic acid group toxins, aluminiumneoaspergillin (1), zirconiumneoaspergillin (2), aspergilliamide (3), ferrineoaspergillin (5), flavacol (6), neoaspergillic acid (7), and three ochratoxins, ochratoxin A n-butyl ester (4), ochratoxin A (8), ochratoxin A methyl ester (9), were isolated from the fermentation broth of marine gorgonian derived fungus Aspergillus sp. SCSGAF0093. Four of them (1-4) were new mycotoxins, and their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. The bio-toxicity of compounds 1-9 were determined by brine shrimp lethality bioassay with median lethal concentration (LC50) values of 2.59-205.67 mu M. This was the first report about zirconium complex obtained from nature and ochratoxins isolated from marine environment. (c) 2012 Elsevier Ltd. All rights reserved.
DepartmentLMB
KeywordMarine-derived Fungus ASp.rgillus Sp. Mycotoxins Aspergillic Acid Group Ochratoxins Brine Shrimp Toxicity
Subject AreaFood Science & Technology ; Toxicology
Funding OrganizationThe authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support.
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Language英语
Funding OrganizationThe authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. ; The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support.
WOS IDWOS:000322924700008
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Cited Times:19[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11055
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorshuhuaqi@scsio.ac.cn
Recommended Citation
GB/T 7714
[Xu, Xinya,He, Fei,Zhang, Xiaoyong,et al. New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093[J]. FOOD AND CHEMICAL TOXICOLOGY,2013,53:46-51.
APA [Xu, Xinya.,He, Fei.,Zhang, Xiaoyong.,Bao, Jie.,Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.,...&shuhuaqi@scsio.ac.cn.(2013).New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093.FOOD AND CHEMICAL TOXICOLOGY,53,46-51.
MLA [Xu, Xinya,et al."New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093".FOOD AND CHEMICAL TOXICOLOGY 53(2013):46-51.
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