Marine Natural Products with Anti-HIV Activities in the Last Decade
[Zhou, Xuefeng; Liu, Juan; Yang, Bin; Lin, Xiuping; Yang, Xian-Wen; Liu, Yonghong] Chinese Acad Sci, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, South China Sea Inst Oceanol,RNAM Ctr Marine Micr, Guangzhou 510301, Guangdong, Peoples R China; yonghongliu@scsio.ac.cn
2013
发表期刊CURRENT MEDICINAL CHEMISTRY
ISSN0929-8673
卷号20期号:7页码:953-973
摘要Marine organisms have been proven to be excellent sources of biologically active compounds against HIV. This review gives an overview of 132 natural products from marine sources obtained during the last decade (2002-2011), which exhibit anti-HIV activity toward different biological targets. Sponges contribute more than half of all anti-HIV natural products from marine organisms, mainly as alkaloids and cyclic depsipeptides. In addition, some macromolecules are considered as potential anti-HIV agents, including lectins from algae and marine invertebrates, as well as sulfated polysaccharides from algae. In the reviewed marine natural products, many active ingredients act as HIV entry inhibitors, one class of new anti-HIV agents, and may be regarded as potential candidates for the development of novel anti-HIV agents. The other features of development in the marine original anti-HIV natural products in this ten years are also discussed.
部门归属LMB
关键词Anti-hiv Hiv Entry Inhibitors Last Decade Marine Organisms Natural Products Sponges
学科领域Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Pharmacology & Pharmacy
资助者This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019).
URL查看原文
语种英语
资助者This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019). ; This work was supported by grants from the National Natural Science Foundation of China (20902094 and 30973679, 21172230), National High Technology Research and Development Program of China (863 Program, 2012AA092104), National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), and Knowledge Innovation Program of Chinese Academy of Sciences (SQ201019).
WOS记录号WOS:000316610600009
引用统计
被引频次:31[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/11063
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn
推荐引用方式
GB/T 7714
[Zhou, Xuefeng,Liu, Juan,Yang, Bin,et al. Marine Natural Products with Anti-HIV Activities in the Last Decade[J]. CURRENT MEDICINAL CHEMISTRY,2013,20(7):953-973.
APA [Zhou, Xuefeng.,Liu, Juan.,Yang, Bin.,Lin, Xiuping.,Yang, Xian-Wen.,...&yonghongliu@scsio.ac.cn.(2013).Marine Natural Products with Anti-HIV Activities in the Last Decade.CURRENT MEDICINAL CHEMISTRY,20(7),953-973.
MLA [Zhou, Xuefeng,et al."Marine Natural Products with Anti-HIV Activities in the Last Decade".CURRENT MEDICINAL CHEMISTRY 20.7(2013):953-973.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Marine Natural Produ(1383KB) 开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。