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学科主题: Chemistry, Organic
题名: Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea
作者: [Sun, Jian-Fan ; Zhou, Xue-Feng ; Yang, Bin ; Lin, Xiuping ; Liu, Juan ; Peng, Yan ; Yang, Xian-Wen ; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, RNAM Ctr Marine Microbiol,Guangdong Key Lab Marin, Guangzhou 510301, Guangdong, Peoples R China ; [Sun, Jian-Fan] Jiangsu Univ, Sch Environm, Zhenjiang 212013, Peoples R China ; [Han, Zhuang] Hong Kong Univ Sci & Technol, Div Life Sci, Sect Marine Ecol & Biotechnol, KAUST Global Acad Partnership Program, Hong Kong, Hong Kong, Peoples R China
通讯作者: yong-hongliu@scsio.ac.cn
关键词: Dichotella gemmacea ; Antifouling agents ; Nontoxic ; Natural products ; Diterpenoids ; Structure elucidation
刊名: TETRAHEDRON
发表日期: 2013
卷: 69, 期:2, 页:871-880
部门归属: LMB
资助者: This study was supported by the National Basic Research Program of China (973 Program, Nos. 2010CB833800 and 2011CB915503), the National High Technology Research and Development Program (863 Program, 2012AA092104), Knowledge Innovation Program of Chinese Academy of Science (KSCX2-YW-G-073 and KSCX2-EW-G-12B), and National Natural Science Foundation of China (Nos. 30973679, 20902094, 21172230, 41176148, 21002110).Guangdong Province-CAS Joint Research Program (2011B0 90300023), Guangdong Province Marine and Fishery Special Project for Science and Technology Popularization (A201101F03), the start-up grant from Jiangsu University (11JDG1147).
摘要: Our continued investigation on the South China Sea gorgonian Dichotella gemmacea led to the isolation of 16 new briarane-type diterpenoids, dichotellides F-U (1-16), along with 18 known analogues (17-34). Their structures were determined by MS, 1D and 2D NMR spectra analyses and by comparison with those reported in literature. The absolute configuration of 15 was confirmed by single-crystal X-ray diffraction data. The antifouling test showed that compounds 3, 4, 6-11, 16, and 23 had potent antifouling activities at nontoxic concentrations with EC50 values of 4.1, 1.82, 6.3, 7.6, 4.6, 1.2, 5.6, 0.79, 2.0, and 0.2 mu g/mL, respectively. (c) 2012 Elsevier Ltd. All rights reserved.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000314371800062
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11072
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
[Sun, Jian-Fan; Zhou, Xue-Feng; Yang, Bin; Lin, Xiuping; Liu, Juan; Peng, Yan; Yang, Xian-Wen; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, RNAM Ctr Marine Microbiol,Guangdong Key Lab Marin, Guangzhou 510301, Guangdong, Peoples R China; [Sun, Jian-Fan] Jiangsu Univ, Sch Environm, Zhenjiang 212013, Peoples R China; [Han, Zhuang] Hong Kong Univ Sci & Technol, Div Life Sci, Sect Marine Ecol & Biotechnol, KAUST Global Acad Partnership Program, Hong Kong, Hong Kong, Peoples R China.Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea,TETRAHEDRON,2013,69(2):871-880
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