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Chemical Constituents of the Sponge Mycale Species from South China Sea
[Zhou, Xuefeng; Lin, Xiuping; Yang, Bin; Yang, Xian-Wen; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China; [Guo, Xieyang] Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China; yonghongliu@scsio.ac.cn
2013
Source PublicationRECORDS OF NATURAL PRODUCTS
ISSN1307-6167
Volume7Issue:2Pages:119-123
AbstractChemical investigation of the sponge Mycale species from the South China Sea afforded eleven known compounds, henicosanoic acid methyl ester (1), hexadecyl ethers of glycerol (2), N-docosanoyl-D-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (3), dibutyl phthalate (4), cholesterol (5), 5 alpha,8 alpha-epidioxycholest-6,22-dien-3 beta-ol (6), 5-hexadecyl-pyrrole-2-carboxaldehyde (7), benzoic acid (8), 4-hydroxybenzoic acid (9), thymine (10), and uracil (11) Compounds 1-4, 6-9 were obtained from the sponge of the genus Mycale for the first time, and 4 and 6 showed toxicity in the brine shrimp lethality test with the LD50 values at 2.9 mu g/mL and 4.7 mu g/mL, respectively.
DepartmentLMB
KeywordSponge Mycale Species Chemical Constituents Brine Shrimp Lethality Test
Subject AreaPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal
Funding OrganizationThis work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources.
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Language英语
Funding OrganizationThis work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources.
WOS IDWOS:000319555800007
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11074
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authoryonghongliu@scsio.ac.cn
Recommended Citation
GB/T 7714
[Zhou, Xuefeng,Lin, Xiuping,Yang, Bin,et al. Chemical Constituents of the Sponge Mycale Species from South China Sea[J]. RECORDS OF NATURAL PRODUCTS,2013,7(2):119-123.
APA [Zhou, Xuefeng.,Lin, Xiuping.,Yang, Bin.,Yang, Xian-Wen.,Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China.,...&yonghongliu@scsio.ac.cn.(2013).Chemical Constituents of the Sponge Mycale Species from South China Sea.RECORDS OF NATURAL PRODUCTS,7(2),119-123.
MLA [Zhou, Xuefeng,et al."Chemical Constituents of the Sponge Mycale Species from South China Sea".RECORDS OF NATURAL PRODUCTS 7.2(2013):119-123.
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