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学科主题: Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal
题名: Chemical Constituents of the Sponge Mycale Species from South China Sea
作者: [Zhou, Xuefeng ; Lin, Xiuping ; Yang, Bin ; Yang, Xian-Wen ; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China ; [Guo, Xieyang] Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China
通讯作者: yonghongliu@scsio.ac.cn
关键词: Sponge Mycale species ; Chemical constituents ; Brine shrimp lethality test
刊名: RECORDS OF NATURAL PRODUCTS
发表日期: 2013
卷: 7, 期:2, 页:119-123
部门归属: LMB
资助者: This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources.
摘要: Chemical investigation of the sponge Mycale species from the South China Sea afforded eleven known compounds, henicosanoic acid methyl ester (1), hexadecyl ethers of glycerol (2), N-docosanoyl-D-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (3), dibutyl phthalate (4), cholesterol (5), 5 alpha,8 alpha-epidioxycholest-6,22-dien-3 beta-ol (6), 5-hexadecyl-pyrrole-2-carboxaldehyde (7), benzoic acid (8), 4-hydroxybenzoic acid (9), thymine (10), and uracil (11) Compounds 1-4, 6-9 were obtained from the sponge of the genus Mycale for the first time, and 4 and 6 showed toxicity in the brine shrimp lethality test with the LD50 values at 2.9 mu g/mL and 4.7 mu g/mL, respectively.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000319555800007
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11074
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
[Zhou, Xuefeng; Lin, Xiuping; Yang, Bin; Yang, Xian-Wen; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China; [Guo, Xieyang] Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China.Chemical Constituents of the Sponge Mycale Species from South China Sea,RECORDS OF NATURAL PRODUCTS,2013,7(2):119-123
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