Chemical Constituents of the Sponge Mycale Species from South China Sea
[Zhou, Xuefeng; Lin, Xiuping; Yang, Bin; Yang, Xian-Wen; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China; [Guo, Xieyang] Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China; yonghongliu@scsio.ac.cn
2013
发表期刊RECORDS OF NATURAL PRODUCTS
ISSN1307-6167
卷号7期号:2页码:119-123
摘要Chemical investigation of the sponge Mycale species from the South China Sea afforded eleven known compounds, henicosanoic acid methyl ester (1), hexadecyl ethers of glycerol (2), N-docosanoyl-D-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (3), dibutyl phthalate (4), cholesterol (5), 5 alpha,8 alpha-epidioxycholest-6,22-dien-3 beta-ol (6), 5-hexadecyl-pyrrole-2-carboxaldehyde (7), benzoic acid (8), 4-hydroxybenzoic acid (9), thymine (10), and uracil (11) Compounds 1-4, 6-9 were obtained from the sponge of the genus Mycale for the first time, and 4 and 6 showed toxicity in the brine shrimp lethality test with the LD50 values at 2.9 mu g/mL and 4.7 mu g/mL, respectively.
部门归属LMB
关键词Sponge Mycale Species Chemical Constituents Brine Shrimp Lethality Test
学科领域Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal
资助者This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources.
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语种英语
资助者This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources. ; This work was supported by the Knowledge Innovation Program of Chinese Academy of Sciences (KSCX2-YW-G-073, SQ201019, KSCX2-EW-G-12B), National Basic Research Program of China (973)'s Project (2011CB915503 and 2010CB833800), National Natural Science Foundation of China (No. 20902094 and 30973679), Open Funds of Key Laboratory of Marine and Estuarine Fisheries Resources and Ecology, Ministry of Agriculture, and Open Funds of Hubei Key Laboratory of Natural Medicinal Chemistry and Evaluation of Resources.
WOS记录号WOS:000319555800007
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/11074
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn
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[Zhou, Xuefeng,Lin, Xiuping,Yang, Bin,et al. Chemical Constituents of the Sponge Mycale Species from South China Sea[J]. RECORDS OF NATURAL PRODUCTS,2013,7(2):119-123.
APA [Zhou, Xuefeng.,Lin, Xiuping.,Yang, Bin.,Yang, Xian-Wen.,Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China.,...&yonghongliu@scsio.ac.cn.(2013).Chemical Constituents of the Sponge Mycale Species from South China Sea.RECORDS OF NATURAL PRODUCTS,7(2),119-123.
MLA [Zhou, Xuefeng,et al."Chemical Constituents of the Sponge Mycale Species from South China Sea".RECORDS OF NATURAL PRODUCTS 7.2(2013):119-123.
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