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学科主题: Chemistry, Medicinal
题名: Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouense Tseng et Lu
作者: [Peng, Yan ; Fredimoses, Mangaladoss ; Yang, Xianwen ; Zhou, Xuefeng ; Yang, Bin ; Lin, Xiuping ; Liu, Juan ; Liu, Yonghong] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,S China Sea Inst Oceano, Guangzhou 510301, Guangdong, Peoples R China ; [Xie, Enyi] Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524025, Peoples R China ; [Zheng, Kai ; Wang, Yifei] Jinan Univ, Guangzhou Jinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China
通讯作者: py00_2006@126.com ; xieenyi@163.com ; twangyf@jnu.edu.cn ; moses10c@gmail.com ; xwyang@scsio.ac.cn ; xfzhou@scsio.ac.cn ; twangyf@jnu.edu.cn ; binggo525@163.com ; xiupinglin@hotmail.com ; ljuan2010@qq.com ; yonghongliu@scsio.ac.cn
关键词: Sargassum naozhouense ; seaweed ; chemical composition ; antiviral activity
刊名: MARINE DRUGS
发表日期: 2013
卷: 11, 期:1, 页:20-32
部门归属: LMB
资助者: This study was supported by the National Basic Research Program of China (973 Program, Nos. 2010CB833800 and 2011CB915503), the National High Technology Research and Development Program (863 Program, 2012AA092104) and the National Natural Science Foundation of China (Nos. 30973679, 21172230, 31270402, and 21002110), Guangdong Province-CAS Joint Research Program (2011B090300023).
摘要: Sargassum naozhouense is a brown seaweed used in folk medicine and applied for thousands of years in Zhanjiang, Guangdong province, China. This study is the first time to investigate its chemical composition and antiviral activity. On the dry weight basis, this seaweed was constituted of ca. 35.18% ash, 11.20% protein, 1.06% lipid and 47.73% total carbohydrate, and the main carbohydrate was water-soluble polysaccharide. The protein analysis indicated the presence of essential amino acids, which accounted for 36.35% of the protein. The most abundant fatty acids were C14:0, C16:0, C18:1 and C20:4. The ash fraction analysis indicated that essential minerals and trace elements, such as Fe, Zn and Cu, were present in the seaweed. IR analysis revealed that polysaccharides from cultivated S. naozhouense may be alginates and fucoidan. The polysaccharides possessed strong antiviral activity against HSV-1 in vitro with EC50 of 8.92 mu g/mL. These results demonstrated cultivated S. naozhouense has a potential for its use in functional foods and antiviral new drugs.
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000314040300002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/11081
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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[Peng, Yan; Fredimoses, Mangaladoss; Yang, Xianwen; Zhou, Xuefeng; Yang, Bin; Lin, Xiuping; Liu, Juan; Liu, Yonghong] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,S China Sea Inst Oceano, Guangzhou 510301, Guangdong, Peoples R China; [Xie, Enyi] Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524025, Peoples R China; [Zheng, Kai; Wang, Yifei] Jinan Univ, Guangzhou Jinan Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China.Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouense Tseng et Lu,MARINE DRUGS,2013,11(1):20-32
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