Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis
[Li, Bo; Shen, Yun-Heng; Fu, Ka-Li; Yue, Rong-Cai; Han, Zhu-Zhen; Yuan, Hu; Liu, Qing-Xin; Shan, Lei; Li, Hui-Liang; Yang, Xian-Wen; Zhang, Wei-Dong] Second Mil Med Univ, Sch Pharm, Dept Phytochem, Shanghai 200433, Peoples R China; Kong, De-Yun] Shanghai Inst Pharmaceut Ind, State Key Lab New Drug & Pharmaceut Proc, Shanghai 200040, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Zhang, Wei-Dong] E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China; shenyunheng9217018@yahoo.com.cn; wdzhangy@hotmail.com
2013
发表期刊CHEMICAL COMMUNICATIONS
ISSN1359-7345
卷号49期号:12页码:1187-1189
摘要A phytochemical investigation of the cone of Pseudolarix amabilis led to the isolation of pseudolarenone (1), a structurally novel pentacyclic (5/11/5/6/5) nortriterpenoid lactone with an unprecedented carbon skeleton featuring a unique bicyclo[8.2.1]tridecane core. Its structure and absolute configurations were elucidated by spectroscopic analysis and single crystal X-ray diffraction (CuK alpha).
部门归属LMB
学科领域Chemistry, Multidisciplinary
资助者This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06).
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语种英语
资助者This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06).
WOS记录号WOS:000313531600011
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被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/11085
专题中科院海洋生物资源可持续利用重点实验室
通讯作者shenyunheng9217018@yahoo.com.cn; wdzhangy@hotmail.com
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[Li, Bo,Shen, Yun-Heng,Fu, Ka-Li,et al. Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis[J]. CHEMICAL COMMUNICATIONS,2013,49(12):1187-1189.
APA [Li, Bo.,Shen, Yun-Heng.,Fu, Ka-Li.,Yue, Rong-Cai.,Han, Zhu-Zhen.,...&wdzhangy@hotmail.com.(2013).Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis.CHEMICAL COMMUNICATIONS,49(12),1187-1189.
MLA [Li, Bo,et al."Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis".CHEMICAL COMMUNICATIONS 49.12(2013):1187-1189.
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