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Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis
[Li, Bo; Shen, Yun-Heng; Fu, Ka-Li; Yue, Rong-Cai; Han, Zhu-Zhen; Yuan, Hu; Liu, Qing-Xin; Shan, Lei; Li, Hui-Liang; Yang, Xian-Wen; Zhang, Wei-Dong] Second Mil Med Univ, Sch Pharm, Dept Phytochem, Shanghai 200433, Peoples R China; Kong, De-Yun] Shanghai Inst Pharmaceut Ind, State Key Lab New Drug & Pharmaceut Proc, Shanghai 200040, Peoples R China; [Yang, Xian-Wen] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Zhang, Wei-Dong] E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China; shenyunheng9217018@yahoo.com.cn; wdzhangy@hotmail.com
2013
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume49Issue:12Pages:1187-1189
AbstractA phytochemical investigation of the cone of Pseudolarix amabilis led to the isolation of pseudolarenone (1), a structurally novel pentacyclic (5/11/5/6/5) nortriterpenoid lactone with an unprecedented carbon skeleton featuring a unique bicyclo[8.2.1]tridecane core. Its structure and absolute configurations were elucidated by spectroscopic analysis and single crystal X-ray diffraction (CuK alpha).
DepartmentLMB
Subject AreaChemistry, Multidisciplinary
Funding OrganizationThis work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06).
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Language英语
Funding OrganizationThis work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06). ; This work was supported by program NCET Foundation, NSFC (81230090), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCM CANCER Project 230232), Key Laboratory of Drug Research for Special Environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (09DZ1975700, 09DZ1971500, 10DZ1971700, 11DZ1970602), National Major Project of China (2011ZX09307-002-03), National Key Technology R&D Program of China (2012BAI29B06).
WOS IDWOS:000313531600011
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/11085
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorshenyunheng9217018@yahoo.com.cn; wdzhangy@hotmail.com
Recommended Citation
GB/T 7714
[Li, Bo,Shen, Yun-Heng,Fu, Ka-Li,et al. Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis[J]. CHEMICAL COMMUNICATIONS,2013,49(12):1187-1189.
APA [Li, Bo.,Shen, Yun-Heng.,Fu, Ka-Li.,Yue, Rong-Cai.,Han, Zhu-Zhen.,...&wdzhangy@hotmail.com.(2013).Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis.CHEMICAL COMMUNICATIONS,49(12),1187-1189.
MLA [Li, Bo,et al."Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis".CHEMICAL COMMUNICATIONS 49.12(2013):1187-1189.
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