Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce
Wang, Junfeng1; Wei, Xiaoyi1; Qin, Xiaochu1; Chen, Hao1; Lin, Xiuping1; Zhang, Tianyu1; Yang, Xianwen1; Liao, Shengrong1; Yang, Bin1; Liu, Juan1; Zhou, Xuefeng1; Tu, Zhengchao1; Liu, Yonghong1; yonghongliu@scsio.ac.cn
2015
发表期刊PHYTOCHEMISTRY LETTERS
卷号12页码:59-62
摘要Two new prenylated phenols vaccinol H (1) and vaccinol I (2), together with three known phenols derivatives 3-5, one glyceride derivative 6, and ergosterol 7 were isolated from endogenous Pestalotiopsis vaccinii (cgmcc3.9199) of mangrove plant Kandelia candel (L.) Druce (Rhizophoraceae). The new structures of 1 and 2 were determined by spectroscopic analyses and circular dichroism (CD) spectra. Most of the isolated compounds (2-6) were tested for their antiviral (EV71), cytotoxic, anti-tuberculosis, and anti-inflammatory effects. Among these compounds, compound 2 exhibited potent COX-2 inhibitory activity with an IC50 value of 16.8 mM. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
部门归属LMB
关键词Pestalotiopsis Vaccinii Structure Elucidation Cox-2 Inhibitory Activity
学科领域Biochemistry & Molecular Biology ; Plant Sciences
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文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/14821
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn
作者单位1.[Wang, Junfeng
2.Lin, Xiuping
3.Yang, Xianwen
4.Liao, Shengrong
5.Yang, Bin
6.Liu, Juan
7.Zhou, Xuefeng
8.Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, Guangzhou 510301, Guangdong, Peoples R China
9.[Wei, Xiaoyi] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
10.[Qin, Xiaochu
11.Zhang, Tianyu
12.Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Mol Engn, Guangzhou 510530, Guangdong, Peoples R China
13.[Qin, Xiaochu
14.Zhang, Tianyu
15.Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Nat Prod Synth, Guangzhou 510530, Guangdong, Peoples R China
16.[Chen, Hao] State Ocean Adm Republ China, Inst Oceanog 1, Key Lab Marine Bioact Subst, Qingdao 266061, Peoples R China
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Wang, Junfeng,Wei, Xiaoyi,Qin, Xiaochu,et al. Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce[J]. PHYTOCHEMISTRY LETTERS,2015,12:59-62.
APA Wang, Junfeng.,Wei, Xiaoyi.,Qin, Xiaochu.,Chen, Hao.,Lin, Xiuping.,...&yonghongliu@scsio.ac.cn.(2015).Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce.PHYTOCHEMISTRY LETTERS,12,59-62.
MLA Wang, Junfeng,et al."Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce".PHYTOCHEMISTRY LETTERS 12(2015):59-62.
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