Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233
Fredimoses, Mangaladoss1; Zhou, Xuefeng1; Ai, Wen1; Tian, Xinpeng1; Yang, Bin1; Lin, Xiuping1; Xian, Jia-Yun1; Liu, Yonghong1; yonghongliu@scsio.ac.cn
2015
发表期刊NATURAL PRODUCT RESEARCH
卷号29期号:2页码:158-162
摘要A new methyl 2-(4-((2-hydroxy-3-methylbut-3-en-1-yl)oxy)phenyl) acetate 1, together with five known compounds 2-6, was isolated from the culture of the deep sea-derived fungus Aspergillus westerdijkiae SCSIO 05233. The new structure was determined by NMR (H-1 and C-13 NMR, HSQC, HMBC and MS) and optical rotation analysis. Compound 5 displayed weak inhibitory activities towards K562 and promyelocytic HL-60 with IC50 values of 25.8 and 44.9 mu M, and compound 6 showed strong antifouling activity with EC50 value 8.81 mu g/mL.
部门归属LMB
关键词Deep Sea Aspergillus Westerdijkiae Cytotoxicity Antifouling
学科领域Chemistry ; Pharmacology & Pharmacy
URL查看原文
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/14881
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn
作者单位1.[Fredimoses, Mangaladoss
2.Zhou, Xuefeng
3.Ai, Wen
4.Tian, Xinpeng
5.Yang, Bin
6.Lin, Xiuping
7.Xian, Jia-Yun
8.Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China
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Fredimoses, Mangaladoss,Zhou, Xuefeng,Ai, Wen,et al. Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233[J]. NATURAL PRODUCT RESEARCH,2015,29(2):158-162.
APA Fredimoses, Mangaladoss.,Zhou, Xuefeng.,Ai, Wen.,Tian, Xinpeng.,Yang, Bin.,...&yonghongliu@scsio.ac.cn.(2015).Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233.NATURAL PRODUCT RESEARCH,29(2),158-162.
MLA Fredimoses, Mangaladoss,et al."Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233".NATURAL PRODUCT RESEARCH 29.2(2015):158-162.
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