Gliomasolides A-E, unusual macrolides from a sponge-derived fungus Gliomastix sp ZSDS1-F7-2
Zhang, Jun1; Lin, Xiu-Ping1; Li, Liang-Chun1; Zhong, Ba-Lian1; Liao, Xiao-Jian1; Liu, Yong-Hong1; Xu, Shi-Hai1; yonghongliu@scsio.ac.cn; txush@jnu.edu.cn
2015
发表期刊RSC ADVANCES
卷号5期号:67页码:54645-54648
摘要Five unusual macrolides, gliomasolides A-E (1-5), were isolated from a sponge-derived fungus Gliomastix sp. ZSDS1-F7-2. Their structures were established by extensive spectroscopic analyses and single-crystal X-ray diffraction studies. Structurally in common, these compounds feature a very rare 14-membered macrocyclic backbone lacking of methyl group. Cytotoxic effect of these metabolites against the growth of HeLa cell lines was evaluated, revealing that 1 exhibited moderate inhibitory effect with an IC50 value of 10.1 mu M.
部门归属LMB
学科领域Chemistry
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文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/14890
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn; txush@jnu.edu.cn
作者单位1.[Zhang, Jun
2.Liao, Xiao-Jian
3.Xu, Shi-Hai] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China
4.[Lin, Xiu-Ping
5.Liu, Yong-Hong] Chinese Acad Sci, Ctr Marine Microbiol, South China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China
6.[Zhong, Ba-Lian] Gannan Normal Univ, Natl Engn Res Ctr Navel Orange, Ganzhou 341000, Peoples R China
7.[Li, Liang-Chun] Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang 621010, Sichuan, Peoples R China
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Zhang, Jun,Lin, Xiu-Ping,Li, Liang-Chun,et al. Gliomasolides A-E, unusual macrolides from a sponge-derived fungus Gliomastix sp ZSDS1-F7-2[J]. RSC ADVANCES,2015,5(67):54645-54648.
APA Zhang, Jun.,Lin, Xiu-Ping.,Li, Liang-Chun.,Zhong, Ba-Lian.,Liao, Xiao-Jian.,...&txush@jnu.edu.cn.(2015).Gliomasolides A-E, unusual macrolides from a sponge-derived fungus Gliomastix sp ZSDS1-F7-2.RSC ADVANCES,5(67),54645-54648.
MLA Zhang, Jun,et al."Gliomasolides A-E, unusual macrolides from a sponge-derived fungus Gliomastix sp ZSDS1-F7-2".RSC ADVANCES 5.67(2015):54645-54648.
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