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A new diketopiperazine derivative from a deep sea-derived Streptomyces sp SCSIO 04496
Luo, Minghe; Tang, Guiling; Ju, Jianhua; Lu, Laichun; Huang, Hongbo; Lu, LC (reprint author), Third Mil Med Univ, Daping Hosp, Inst Surg Res, Dept Pharm, Chongqing 400042, Peoples R China.
2016
Source PublicationNATURAL PRODUCT RESEARCH
Volume30Issue:2Pages:138-143
AbstractA new diketopiperazine (DKP) derivative, (6R,3Z)-3-benzylidene-6-isobutyl-1-methyl piperazine-2,5-dione (1), as well as five known DKPs 2-6 was isolated from a deep sea-derived Streptomyces sp. SCSIO 04496. The structure of 1 was elucidated using a combination of 1D and 2D NMR, HR-ESI-MS and chiral-phase HPLC techniques. Compounds 1-6 did not show cytotoxic activity at a concentration of 100M in bioactivity assay.
Department[Luo, Minghe; Lu, Laichun] Third Mil Med Univ, Daping Hosp, Inst Surg Res, Dept Pharm, Chongqing 400042, Peoples R China; [Luo, Minghe; Tang, Guiling; Ju, Jianhua; Huang, Hongbo] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Materia Medica, CAS Key Lab Trop Marine Bioresources & Ecol,RNAM, Guangzhou 510301, Guangdong, Peoples R China ; LMB
KeywordDiketopiperazine Cyclodipeptide Streptomyces Sp
Subject AreaChemistry ; Pharmacology & Pharmacy
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/15508
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding AuthorLu, LC (reprint author), Third Mil Med Univ, Daping Hosp, Inst Surg Res, Dept Pharm, Chongqing 400042, Peoples R China.
Recommended Citation
GB/T 7714
Luo, Minghe,Tang, Guiling,Ju, Jianhua,et al. A new diketopiperazine derivative from a deep sea-derived Streptomyces sp SCSIO 04496[J]. NATURAL PRODUCT RESEARCH,2016,30(2):138-143.
APA Luo, Minghe,Tang, Guiling,Ju, Jianhua,Lu, Laichun,Huang, Hongbo,&Lu, LC .(2016).A new diketopiperazine derivative from a deep sea-derived Streptomyces sp SCSIO 04496.NATURAL PRODUCT RESEARCH,30(2),138-143.
MLA Luo, Minghe,et al."A new diketopiperazine derivative from a deep sea-derived Streptomyces sp SCSIO 04496".NATURAL PRODUCT RESEARCH 30.2(2016):138-143.
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