Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004
Han, Z; Li, YX; Liu, LL; Lu, L; Guo, XR; Zhang, XX; Zhang, XY; Qi, SH; Xu, Y; Qian, PY; zhuanghan@idsse.ac.cn; liyongxin@connect.ust.hk; leonie@nwsuaf.edu.cn; luliangust@163.com; xianrong.guo@kaust.edu.sa; xixiang.zhang@kaust.edu.sa; zhangxiaoyong@scsio.ac.cn; shuhuaqi@scsio.ac.cn; boxuying@szu.edu.cn; boqianpy@ust.hk
2017
发表期刊MARINE DRUGS
卷号15期号:5页码:128-
摘要Eleven new depsides-thielavins W-Z (1-4) and thielavins Z(1)-Z(7) (5-11)-and also four known thielavins-A, H, J, and K (12-15)-were isolated from the ethyl acetate extract of a marine-derived fungal strain Thielavia sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle Balanus (=Amphibalanus) amphitrite. The results showed that compounds 1-3 and 6-13 were active, with EC50 values ranging from 2.95 +/- 0.59 to 69.19 +/- 9.51 mu M, respectively. The inhibitive effect of compounds 1-3 and 7 was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.
部门归属[Han, Zhuang] Chinese Acad Sci, Inst Deep Sea Sci & Engn, 28 Luhuitou Rd, Sanya 572000, Peoples R China; [Han, Zhuang; Li, Yong-Xin; Liu, Ling-Li; Lu, Liang; Xu, Ying; Qian, Pei-Yuan] Hong Kong Univ Sci & Technol, Div Life Sci, Hong Kong, Hong Kong, Peoples R China; [Guo, Xian-Rong] King Abdullah Univ Sci & Technol, Imaging & Characterizat Core Lab, Thuwal 239556900, Saudi Arabia; [Zhang, Xi-Xiang] King Abdullah Univ Sci & Technol, Phys Sci & Engn, Thuwal 239556900, Saudi Arabia; [Zhang, Xiao-Yong; Qi, Shu-Hua] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China; [Xu, Ying] Shenzhen Univ, Coll Life Sci, 3688 Nanhai Ave, Shenzhen 518060, Peoples R China
关键词Marine-derived Fungus Thielavia Sp. Antifouling Balanus (=amphiBalanus) Amphitrite Thielavins
资助项目LMB
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/16283
专题中科院海洋生物资源可持续利用重点实验室
通讯作者zhuanghan@idsse.ac.cn; liyongxin@connect.ust.hk; leonie@nwsuaf.edu.cn; luliangust@163.com; xianrong.guo@kaust.edu.sa; xixiang.zhang@kaust.edu.sa; zhangxiaoyong@scsio.ac.cn; shuhuaqi@scsio.ac.cn; boxuying@szu.edu.cn; boqianpy@ust.hk
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Han, Z,Li, YX,Liu, LL,et al. Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004[J]. MARINE DRUGS,2017,15(5):128-.
APA Han, Z.,Li, YX.,Liu, LL.,Lu, L.,Guo, XR.,...&boqianpy@ust.hk.(2017).Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004.MARINE DRUGS,15(5),128-.
MLA Han, Z,et al."Thielavins W-Z(7), New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp UST030930-004".MARINE DRUGS 15.5(2017):128-.
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