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Angucycline Glycosides from Mangrove-Derived Streptomyces diastaticus subsp SCSIO GJ056
Gui, C; Liu, YN; Zhou, ZB; Zhang, SW; Hu, YF; Gu, YC; Huang, HB; Ju, JH; guichun1988@sina.com; LIUYN@sysucc.org.cn; zzb1881396@163.com; sherry920111@163.com; yunfeng.hu@scsio.ac.cn; yucheng.gu@syngenta.com; huanghb@scsio.ac.cn; jju@scsio.ac.cn
2018
Source PublicationMARINE DRUGS
Volume16Issue:6Pages:-185
AbstractNine new angucycline glycosides designated urdamycins N1-N9 (1-9), together with two known congener urdamycins A (10) and B (11), were obtained from a mangrove-derived Streptomycesdiastaticus subsp. SCSIO GJ056. The structures of new compounds were elucidated on the basis of extensive spectroscopic data analysis. The absolute configurations of 6-9 were assigned by electronic circular dichroism calculation method. Urdamycins N7 (7) and N8 (8) represent the first naturally occurring (5R, 6R)-angucycline glycosides, which are diastereomers of urdamycins N6 (6) and N9 (9), respectively.
Department[Gui, Chun; Zhou, Zhenbin; Zhang, Shanwen; Hu, Yunfeng; Huang, Hongbo; Ju, Jianhua] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China; [Gui, Chun; Zhou, Zhenbin; Zhang, Shanwen; Ju, Jianhua] Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 110039, Peoples R China; [Liu, Yena] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, Ctr Canc, Guangzhou 510060, Guangdong, Peoples R China; [Gu, Yu-Cheng] Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
Subject AreaPharmacology & Pharmacy
WOS Keywordmangrove-derived Streptomyces ; angucycline ; urdamycin
Funding ProjectLMB
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/16937
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorguichun1988@sina.com; LIUYN@sysucc.org.cn; zzb1881396@163.com; sherry920111@163.com; yunfeng.hu@scsio.ac.cn; yucheng.gu@syngenta.com; huanghb@scsio.ac.cn; jju@scsio.ac.cn
Recommended Citation
GB/T 7714
Gui, C,Liu, YN,Zhou, ZB,et al. Angucycline Glycosides from Mangrove-Derived Streptomyces diastaticus subsp SCSIO GJ056[J]. MARINE DRUGS,2018,16(6):-185.
APA Gui, C.,Liu, YN.,Zhou, ZB.,Zhang, SW.,Hu, YF.,...&jju@scsio.ac.cn.(2018).Angucycline Glycosides from Mangrove-Derived Streptomyces diastaticus subsp SCSIO GJ056.MARINE DRUGS,16(6),-185.
MLA Gui, C,et al."Angucycline Glycosides from Mangrove-Derived Streptomyces diastaticus subsp SCSIO GJ056".MARINE DRUGS 16.6(2018):-185.
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