SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室
Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection
Luo, P; Liu, QT; Deng, YQ; Tian, YS; Yun, L; Hu, CQ; huchaoqun62@163.com
2018
Source PublicationMARINE GENOMICS
Volume38Pages:5-8
AbstractRNA-Seq transcriptome analysis of bacteria during phage infection has been occasionally reported in last several years but little is known about how Vibrio bacteria respond to phage invasion on global transcriptome level. In the present study, transcriptome profiling of V. alginolyticus during a lytic phage infection was first investigated through strand-specific RNA-Seq analysis. The results revealed that 346 unigenes were up-regulated and 860 unigenes were down-regulated during the infection of phage Vp670. Notably, the unigenes involving in phosphorelay signal transduction system were largely down-regulated in infected V. alginolyticus cells. However, some unigenes in the GO terms (DNA binding and sequence-specific DNA binding transcription factor activity) were up-regulated including a csp gene coding cold shock protein. These transcriptome data contribute to a more comprehensive insight into cellular response of V. alginolyticus to phage infection and help us deeply understand the phage-host interplay on molecular levels. (C) 2017 Elsevier B.V. All rights reserved.
Department[Luo, Peng; Liu, Qiuting; Deng, Yiqin; Tian, Yushun; Yun, Long; Hu, Chaoqun] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Prov Key Lab Appl Marine Biol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China; [Luo, Peng; Hu, Chaoqun] South China Sea Bioresource Exploitat & Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Liu, Qiuting; Deng, Yiqin; Tian, Yushun; Yun, Long] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Subject AreaGenetics & Heredity ; Marine & Freshwater Biology
WOS KeywordTranscriptome ; Vibrio alginolyticus ; Phage infection ; Differential expression genes
Funding ProjectLMB
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/16973
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorhuchaoqun62@163.com
Recommended Citation
GB/T 7714
Luo, P,Liu, QT,Deng, YQ,et al. Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection[J]. MARINE GENOMICS,2018,38:5-8.
APA Luo, P.,Liu, QT.,Deng, YQ.,Tian, YS.,Yun, L.,...&huchaoqun62@163.com.(2018).Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection.MARINE GENOMICS,38,5-8.
MLA Luo, P,et al."Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection".MARINE GENOMICS 38(2018):5-8.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.