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Enzymatic Synthesis of GDP-alpha-L-fucofuranose by MtdL and Hyg20
Qin, XJ; Xie, YC; Huang, HB; Chen, Q; Ma, JY; Li, QL; Ju, JH;
Source PublicationORGANIC LETTERS
AbstractTwo mutases, MtdL and Hyg20, are reported. Both are able to functionally drive the biosynthesis of GDP-alpha-L-fucofuranose. Both enzymes catalyze similar functions, catalytically enabling the bidirectional reaction between GDP-beta-L-fucopyranose and GDP-alpha-L-fucofuranose using only divalent cations as cofactors. This realization is but one of a number of important insights into fucofuranose biosynthesis presented herein.
Department[Qin, Xiangjing; Xie, Yunchang; Huang, Hongbo; Chen, Qi; Ma, Junying; Li, Qinglian; Ju, Jianhua] Chinese Acad Sci, RNAM Ctr Marine Microbiol, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China; [Ju, Jianhua] Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 110039, Peoples R China
Subject AreaChemistry
Funding ProjectLMB
Document Type期刊论文
Recommended Citation
GB/T 7714
Qin, XJ,Xie, YC,Huang, HB,et al. Enzymatic Synthesis of GDP-alpha-L-fucofuranose by MtdL and Hyg20[J]. ORGANIC LETTERS,2018,20(4):1015-1018.
APA Qin, XJ.,Xie, YC.,Huang, HB.,Chen, Q.,Ma, JY.,...& Synthesis of GDP-alpha-L-fucofuranose by MtdL and Hyg20.ORGANIC LETTERS,20(4),1015-1018.
MLA Qin, XJ,et al."Enzymatic Synthesis of GDP-alpha-L-fucofuranose by MtdL and Hyg20".ORGANIC LETTERS 20.4(2018):1015-1018.
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