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Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp SCSI0041218
Yang, B; Tao, HM; Lin, XP; Wang, JF; Liao, SR; Dong, JD; Zhou, XF; Liu, YH; xfzhou@scsio.ac.cn; yonghongliu@scsio.ac.cn
2018
Source PublicationTETRAHEDRON
Volume74Issue:1Pages:77-82
AbstractFour new prenylated indole alkaloids (1-4), and four new chromone derivatives (7-10), together with six known compounds (5, 6, and 11-14), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSI0041218, cultured in the 1% NaCI PDB substrate. The structures of new compounds were determined by analysis of the NMR and MS spectroscopic data. The absolute configuration of the prenylated indole alkaloids were elucidated based on the comparison of ECDs with known analogues. The absolute configurations of the chromone derivatives were determined by time-dependent density functional theory calculations of the ECD spectra. In all of these isolated compounds, penixanthones A and B (12 and 13) exhibited antiallergic activities in vitro. (C) 2017 Elsevier Ltd. All rights reserved.
Department[Yang, Bin; Lin, Xiuping; Wang, Junfeng; Liao, Shengrong; Dong, Junde; Zhou, Xuefeng; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China; [Tao, Huaming] Southern Med Univ, Sch Tradit Chinese Med, Guangzhou 510515, Guangdong, Peoples R China
Subject AreaChemistry
WOS KeywordPenicillium sp mangrovamide ; Prenylated indole alkaloid ; Chromone ; Anti-allergic activity
Funding ProjectLMB
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17017
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorxfzhou@scsio.ac.cn; yonghongliu@scsio.ac.cn
Recommended Citation
GB/T 7714
Yang, B,Tao, HM,Lin, XP,et al. Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp SCSI0041218[J]. TETRAHEDRON,2018,74(1):77-82.
APA Yang, B.,Tao, HM.,Lin, XP.,Wang, JF.,Liao, SR.,...&yonghongliu@scsio.ac.cn.(2018).Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp SCSI0041218.TETRAHEDRON,74(1),77-82.
MLA Yang, B,et al."Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp SCSI0041218".TETRAHEDRON 74.1(2018):77-82.
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