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Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp SCSIO41007
Pang, XY; Lin, XP; Wang, JF; Liang, R; Tian, YQ; Salendra, L; Luo, XW; Zhou, XF; Yang, B; Tu, ZC; Liu, YH; wangjunfeng@scsio.ac.cn; yonghongliu@scsio.ac.cn
2018
Source PublicationSTEROIDS
Volume129Pages:41-46
AbstractThree new highly oxygenated sterols (1-3) and a new dihydroisocoumarin (7) together with six known compounds were isolated from the extracts of the culture of a sponge-derived fungus Cladosporium sp. SCSIO41007. The structures of all new compounds (1-3, 7) were determined by the extensive spectroscopic analysis including NMR, MS, IR, and W. Their absolute configurations were determined by X-ray single-crystal and CD data analysis. Compound 2 exhibited weak inhibitory activity against H3N2 with the IC50 value of 16.2 mu M.
Department[Pang, Xiaoyan; Lin, Xiuping; Wang, Junfeng; Tian, Yongqi; Salendra, Limbadri; Luo, Xiaowei; Zhou, Xuefeng; Yang, Bin; Liu, Yonghong] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou, Guangdong, Peoples R China; [Pang, Xiaoyan; Tian, Yongqi; Salendra, Limbadri; Luo, Xiaowei; Liu, Yonghong] Univ Chinese Acad Sci, Beijing, Peoples R China; [Liang, Rui; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed, Lab Mol Engn, Guangzhou, Guangdong, Peoples R China; [Liang, Rui; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed, Lab Nat Prod Synth, Guangzhou, Guangdong, Peoples R China; [Liang, Rui; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Hlth, Lab Mol Engn, Guangzhou, Guangdong, Peoples R China; [Liang, Rui; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Hlth, Lab Nat Prod Synth, Guangzhou, Guangdong, Peoples R China; [Liu, Yonghong] South China Sea Bioresource Exploitat & Utilizat, Guangzhou, Guangdong, Peoples R China
Subject AreaBiochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS KeywordSponge-derived fungus ; Cladosporium sp. ; Antiviral ; Sterols
Funding ProjectLMB
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17035
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorwangjunfeng@scsio.ac.cn; yonghongliu@scsio.ac.cn
Recommended Citation
GB/T 7714
Pang, XY,Lin, XP,Wang, JF,et al. Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp SCSIO41007[J]. STEROIDS,2018,129:41-46.
APA Pang, XY.,Lin, XP.,Wang, JF.,Liang, R.,Tian, YQ.,...&yonghongliu@scsio.ac.cn.(2018).Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp SCSIO41007.STEROIDS,129,41-46.
MLA Pang, XY,et al."Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp SCSIO41007".STEROIDS 129(2018):41-46.
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