SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室
New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity
Bao, Jie1; He, Fei; Yu, Jin-Hai; Zhai, Huijuan; Cheng, Zhi-Qiang; Jiang, Cheng-Shi; Zhang, Yuying; Zhang, Yun2; Zhang, Xiaoyong3; Chen, Guangying1; Zhang, Hua
2018
Source PublicationMOLECULES
ISSN1420-3049
Volume23Issue:8Pages:1982
AbstractFive new chromone derivatives, arthones A-E (1-5), together with eight known biogenetically related cometabolites (6-13), were isolated from a deep-sea-derived fungus Arthrinium sp. UJNMF0008. Their structures were assigned by detailed analyses of spectroscopic data, while the absolute configurations of 1 and 5 were established by electronic circular dichroism (ECD) calculations and that of 2 was determined by modified Mosher ester method. Compounds 3 and 8 exhibited potent antioxidant property with DPPH and ABTS radical scavenging activities, with IC50 values ranging from 16.9 to 18.7 mu M. Meanwhile, no compounds indicated obvious bioactivity in our antimicrobial and anti-inflammatory assays at 50.0 mu M.
DepartmentLMB
KeywordArthrinium sp. chromone polyketide antioxidant activity
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17648
Collection中科院海洋生物资源可持续利用重点实验室
Affiliation1.Univ Jinan, Sch Biol Sci & Technol, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China
2.Hainan Normal Univ, Minist Educ, Key Lab Trop Med Plant Chem, 99 South Rd Longkun Rd, Haikou 571158, Hainan, Peoples R China
3.Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China
4.South China Agr Univ, Coll Marine Sci, 483 Wushan Rd, Guangzhou 510642, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Bao, Jie,He, Fei,Yu, Jin-Hai,et al. New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity[J]. MOLECULES,2018,23(8):1982.
APA Bao, Jie.,He, Fei.,Yu, Jin-Hai.,Zhai, Huijuan.,Cheng, Zhi-Qiang.,...&Zhang, Hua.(2018).New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity.MOLECULES,23(8),1982.
MLA Bao, Jie,et al."New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity".MOLECULES 23.8(2018):1982.
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