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A new uridine derivative and a new indole derivative from the coral-associated actinomycete Pseudonocardia sp. SCSIO 11457
Fang, Zhuangjie1; Chen, Siqiang1; Zhu, Yiguang; Li, Jie; Khan, Imran1; Zhang, Qingbo; Zhang, Changsheng1
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
AbstractA new uridine derivative 11457A (1), and a new indole derivative 11457B (2), together with a known compound 1H-indole-2-carbaldehyde (3), were characterized from the fermentation broth of the actinomycete Pseudonocardia sp. SCSIO 11457, an isolate associated with the scleractinian coral Galaxea fascicularis. Upon detailed spectroscopic analysis, 11457A (1) was identified as a uridine analog, and 11457B (2) was elucidated as an indole derivative 2-hydroxy-1-(1H-indol-2-yl)pentane-1,4-dione. Biological evaluation indicated that none of compounds 1-3 showed antibacterial activities against pathogenic bacteria and cytotoxic activities against human cancer cell lines. [GRAPHICS] .
DepartmentLMB
KeywordCoral-associated actinomycete Pseudonocardia sp uridine derivative marine natural products
DOI10.1080/14786419.2019.1616729
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Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17841
Collection中科院海洋生物资源可持续利用重点实验室
Affiliation1.Chinese Acad Sci, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Inst South China Sea Ecol & Environm Engn,South, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Fang, Zhuangjie,Chen, Siqiang,Zhu, Yiguang,et al. A new uridine derivative and a new indole derivative from the coral-associated actinomycete Pseudonocardia sp. SCSIO 11457[J]. NATURAL PRODUCT RESEARCH.
APA Fang, Zhuangjie.,Chen, Siqiang.,Zhu, Yiguang.,Li, Jie.,Khan, Imran.,...&Zhang, Changsheng.
MLA Fang, Zhuangjie,et al."A new uridine derivative and a new indole derivative from the coral-associated actinomycete Pseudonocardia sp. SCSIO 11457".NATURAL PRODUCT RESEARCH
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