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A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218
Huang, Jingxia; She, Jianglian1; Yang, Xiliang1; Liu, Juan2; Zhou, Xuefeng2; Yang, Bin2
2019
Source PublicationMOLECULES
ISSN1420-3049
Volume24Issue:9Pages:1686
AbstractA new macrodiolide, mangrovlide A (1) and two new polycyclic chromones, penixanthones C (2) and D (3), as well as four other known compounds (4-7), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSIO041218, cultured in the 0.25% NaCl rice substrate. The structures of the new compounds were determined by analysis of the NMR and MS spectroscopic data. Compound 1 possesses a 10-membered macrodiolide unit, while 2 and 3 are chromones with an unprecedented 6/6/6/5 polycyclic skeleton. Compounds 1-7 were evaluated for their cytotoxicities, while all the compounds displayed weak or no activity.
DepartmentLMB
Keywordmarine fungus Penicillium sp penixanthone macrodiolide chromone
DOI10.3390/molecules24091686
Citation statistics
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17851
Collection中科院海洋生物资源可持续利用重点实验室
Affiliation1.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
2.Wuhan Univ Sci Technol, Inst Infect Immunol & Tumor Microenvironm, Hubei Prov Key Lab Occupat Hazard Identificat & C, Dept Pharm,Med Coll, Wuhan 430081, Hubei, Peoples R China
3.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Huang, Jingxia,She, Jianglian,Yang, Xiliang,et al. A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218[J]. MOLECULES,2019,24(9):1686.
APA Huang, Jingxia,She, Jianglian,Yang, Xiliang,Liu, Juan,Zhou, Xuefeng,&Yang, Bin.(2019).A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218.MOLECULES,24(9),1686.
MLA Huang, Jingxia,et al."A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218".MOLECULES 24.9(2019):1686.
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