SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室
Sex-biased regulation of respiratory burst, phagocytic activity and plasma immune factors in lined seahorse (Hippocampus erectus) after subchronic benzo[a]pyrene exposure
Jiang, Han; Wang, Kai; Fang, Yan; Chen, Jun; Li, Yanmin1; Xia, Guangbo; Zhang, Yingfeng; Liu, Yu; Ren, Chuanbo2; Lin, Qiang3
2019
Source PublicationFISH & SHELLFISH IMMUNOLOGY
ISSN1050-4648
Volume86Pages:1162
AbstractBoth wild and aquacultured seahorses are currently under great threat from marine pollution, notably from the potent contaminant and carcinogen benzo[a]pyrene (BaP). However, very little data are available regarding the immunomodulating effects of BaP in seahorses. Therefore, in this study, we exposed lined seahorses (Hippocampus erectus) for 7 d to BaP at three dosages (0.5, 5, and 50 mu g/L) to evaluate sexual dimorphism in immune response. We measured eight immune parameters in the blood, including respiratory burst (RB), phagocytic activity (PA), monocytes/leucocytes, immunoglobulin M, complement 3, complement, interferon-a, and interleukin-2. Male seahorses had significantly higher parameters than females, except in terms of monocytes/leucocytes (P < 0.05). Although flow cytometry showed that RB and PA variation per BaP dose were roughly similar across sexes, RB and PA exhibited distinct patterns. Additionally, fluorescence intensity and leucocyte percentage were positively correlated in PA but not RB for all treatment and sex combinations. Through ELISA, we showed that the other six parameters had complex responses that nevertheless varied in a BaP-dosage and sex-dependent manner. Overall, adult male seahorses had higher immunocompetence than females before BaP exposure, and sexual dimorphism continued to be apparent during BaP exposure. Furthermore, all eight parameters were sensitive to BaP. Based on these results, we highly recommend H. erectus as a sentinel species for crude contamination, whereas PA and RB are valuable bioindicators of marine contaminants such as BaP.
DepartmentLMB
KeywordHippocampus erectus Immunocompetence Marine pollution benzo[a]pyrene Sexual dimorphism
DOI10.1016/j.fsi.2018.12.068
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Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/17888
Collection中科院海洋生物资源可持续利用重点实验室
Affiliation1.Ludong Univ, Sch Agr, 186 Hongqing Middle Rd, Yantai 264025, Peoples R China
2.Ludong Univ, Sch Life Sci, Yantai 264025, Peoples R China
3.Shandong Marine Resource & Environm Res Inst, Shandong Prov Key Lab Restorat Marine Ecol, Yantai, Peoples R China
4.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Jiang, Han,Wang, Kai,Fang, Yan,et al. Sex-biased regulation of respiratory burst, phagocytic activity and plasma immune factors in lined seahorse (Hippocampus erectus) after subchronic benzo[a]pyrene exposure[J]. FISH & SHELLFISH IMMUNOLOGY,2019,86:1162, 1168.
APA Jiang, Han.,Wang, Kai.,Fang, Yan.,Chen, Jun.,Li, Yanmin.,...&Lin, Qiang.(2019).Sex-biased regulation of respiratory burst, phagocytic activity and plasma immune factors in lined seahorse (Hippocampus erectus) after subchronic benzo[a]pyrene exposure.FISH & SHELLFISH IMMUNOLOGY,86,1162.
MLA Jiang, Han,et al."Sex-biased regulation of respiratory burst, phagocytic activity and plasma immune factors in lined seahorse (Hippocampus erectus) after subchronic benzo[a]pyrene exposure".FISH & SHELLFISH IMMUNOLOGY 86(2019):1162.
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