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Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus
Qin, Geng1; Zhang, Yuan2; Zhang, Bo1; Zhang, Yanhong1; Liu, Yali1; Lin, Qiang1,2
2020
Source PublicationSCIENCE OF THE TOTAL ENVIRONMENT
ISSN0048-9697
Volume715Pages:136840
AbstractExposure to environmental estrogens and progestins has contributed to adverse effects on the reproduction of many aquatic wildlife species. However, few reports have paid attention to fish species with specialized reproductive strategies, such as male-pregnancy seahorses. In this study, the potential effects on the behavior, gonad and brood pouch development, and transcriptomic profiles of lined seahorse I lippocarnpus erectus exposed to environmentally relevant concentrations of 17 alpha-ethynyl estradiol (EE2, 5 ng/L, 50 ng/L. 10 ng/L, 100 ng/L) or progesterone (P4) for 60 days were examined. Both EE2 and P4 significantly inhibited male brood pouch development by disrupting the extracellular matrix and basement membrane pathways. In addition, both EE2 and P4 impaired the expression of genes associated with spermatogenesis in the testis, and even caused male feminization. We suggest that seahorses be regarded as a sensitive indicator for evaluating the potential effects of endocrine disrupting chemical (EDC) pollution on aquatic biotic communities. (C) 2020 Elsevier B.V. All rights reserved.
DepartmentLMB
Keyword17 alpha-ethynyl estradiol Progesterone Spermatogenesis Male pregnancy Seahorse
Funding OrganizationKey Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407] ; Key Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407]
DOI10.1016/j.scitotenv.2020.136840
Funding OrganizationKey Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407] ; Key Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407]
Citation statistics
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/18439
Collection中科院海洋生物资源可持续利用重点实验室
Affiliation1.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510275, Peoples R China
2.Chinese Acad Sci, Inst South China Sea Ecol & Environm Engn, Guangzhou 510275, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Qin, Geng,Zhang, Yuan,Zhang, Bo,et al. Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,715:136840.
APA Qin, Geng,Zhang, Yuan,Zhang, Bo,Zhang, Yanhong,Liu, Yali,&Lin, Qiang.(2020).Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus.SCIENCE OF THE TOTAL ENVIRONMENT,715,136840.
MLA Qin, Geng,et al."Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus".SCIENCE OF THE TOTAL ENVIRONMENT 715(2020):136840.
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