SCSIO OpenIR  > 广东省海洋药物重点实验室
Exploring novel bioactive compounds from marine microbes
Zhang, LX; An, R; Wang, JP; Sun, N; Zhang, S; Hu, JC; Kuai, J; zhang_lixin@gibh.ac.cn
2005
发表期刊CURRENT OPINION IN MICROBIOLOGY
ISSN1369-5274
卷号8期号:3页码:276-281
摘要The historical paradigm of the deep ocean as a biological 'desert' has shifted to one of a 'rainforest' owing to the isolation of many novel microbes and their associated bioactive compounds. Recently, there has been an explosion of information about novel bioactive compounds that have been isolated from marine microbes in an effort to further explore the relatively untapped marine microbes and their secondary metabolites for drug discovery. The microbes are recovered and purified from the ocean by both conventional and innovative isolation methods to obtain those previously thought to be 'uncultivable'. To overcome the difficulties and limitations associated with cultivation techniques, several DNA-based molecular methods have been developed to bypass the culture-dependent bottleneck. Bioactive compounds isolated using the above strategies have not only shown importance in biotechnological and pharmaceutical applications but have also increased our understanding of the diversity of marine microbiota, ecosystem functions and the exploitable biology.
部门归属Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510663, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Peoples R China; SynerZ Pharmaceut Inc, Lexington, MA 02421 USA; Shandong Univ, Dept Microbiol, Jinan 250100, Peoples R China; Chinese Acad Sci, Inst Appl Ecol, Shenyang 110016, Peoples R China; Wyeth Ayerst Res, Cambridge, MA 02139 USA
学科领域Microbiology
收录类别sci
资助项目广东省海洋药物重点实验室
WOS记录号WOS:000230098000007
引用统计
被引频次:126[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/2241
专题广东省海洋药物重点实验室
通讯作者zhang_lixin@gibh.ac.cn
推荐引用方式
GB/T 7714
Zhang, LX,An, R,Wang, JP,et al. Exploring novel bioactive compounds from marine microbes[J]. CURRENT OPINION IN MICROBIOLOGY,2005,8(3):276-281.
APA Zhang, LX.,An, R.,Wang, JP.,Sun, N.,Zhang, S.,...&zhang_lixin@gibh.ac.cn.(2005).Exploring novel bioactive compounds from marine microbes.CURRENT OPINION IN MICROBIOLOGY,8(3),276-281.
MLA Zhang, LX,et al."Exploring novel bioactive compounds from marine microbes".CURRENT OPINION IN MICROBIOLOGY 8.3(2005):276-281.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Exploring novel bioa(134KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。