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学科主题: Biochemistry & Molecular Biology; Fisheries; Physiology
题名: Effects of dietary riboflavin levels on antioxidant defense of the juvenile grouper Epinephelus coioides
作者: Huang, JW ; Tian, LX ; Wu, XY ; Yang, HJ ; Liu, YJ
通讯作者: Fishnutri@163.com
关键词: Antioxidant defense ; Epinephelus coioides ; Grouper ; Riboflavin
刊名: FISH PHYSIOLOGY AND BIOCHEMISTRY
发表日期: 2010
卷: 36, 期:1, 页:55-62
收录类别: sci
部门归属: [Huang, Junwa; Tian, Lixia; Yang, Huijun; Liu, Yongjian] Sun Yat Sen Univ, Sch Life Sci, Inst Aquat Econ Anim, Guangzhou 510275, Guangdong, Peoples R China; [Wu, Xiangyun] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
项目归属: LMB
摘要: This study was conducted to evaluate the effects of dietary riboflavin on antioxidant defense in the juvenile grouper Epinephelus coioides. Graded levels of riboflavin (0.9, 1.6, 4.4, 6.7, 12.9 and 19.4 mg kg(-1) dry diet) were fed to grouper juveniles (mean weight: 14.90 +/- A 0.46 g) for 12 weeks. Higher levels of liver thiobarbituric acid reactive substances (TBARS) content were observed in grouper fed low doses (0.9 and 1.6 mg kg(-1) diet) of riboflavin. Both liver glutathione reductase (GR) activity and its activation coefficient (GR-AC) poorly responded to riboflavin deficiency. In addition, other indices of the glutathione-dependent defense system, including the activities of glutathione peroxidase (GSH-PX) and glutathione-S-transferase (GST), and the content of glutathione (GSH), were also non-significantly affected by dietary riboflavin levels. However, the activities of liver superoxide dismutase (SOD) and catalase (CAT) were significantly lower in fish fed 0.9 mg kg(-1) diet, with a positive correlation between the different groups. In conclusion, the present study indicated that the juvenile grouper fed the riboflavin-unsupplemented diet was susceptible to lipid peroxidation (LPO), with lower SOD and CAT activities in the liver. However, the glutathione-dependent defense system of grouper was not affected by dietary riboflavin levels.
原文出处: 查看原文
WOS记录号: WOS:000275899400006
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/3874
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Huang, JW; Tian, LX; Wu, XY; Yang, HJ; Liu, YJ.Effects of dietary riboflavin levels on antioxidant defense of the juvenile grouper Epinephelus coioides,FISH PHYSIOLOGY AND BIOCHEMISTRY,2010,36(1):55-62
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