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学科主题: Chemistry, Organic
题名: Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera
作者: He, F ; Pu, JX ; Huang, SX ; Wang, YY ; Xiao, WL ; Li, LM ; Liu, JP ; Zhang, HB ; Li, Y ; Sun, HD
通讯作者: pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
刊名: ORGANIC LETTERS
发表日期: 2010
卷: 12, 期:6, 页:1208-1211
收录类别: sci
部门归属: [He, Fei; Pu, Jian-Xin; Huang, Sheng-Xiong; Wang, Yuan-Yuan; Xiao, Wei-Lie; Li, Li-Mei; Liu, Jing-Ping; Zhang, Hai-Bo; Li, Yan; Sun, Han-Dong] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China; [He, Fei] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresourses Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
项目归属: LMB
摘要: A new cytotoxic triterpenold, schinalactone A (1), together with two new biogenetically related compounds, schinalactones B (2) and C (3), has been isolated from the roots and stems of Schisandra sphenanthera. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 showed significant cytotoxicity against PANC-1 cell lines with IC50 values of 5.9 and 4.1 mu M, respectively, A plausible biosynthetic pathway of 1 was also postulated.
原文出处: 查看原文
WOS记录号: WOS:000275379100017
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/3882
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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He, F; Pu, JX; Huang, SX; Wang, YY; Xiao, WL; Li, LM; Liu, JP; Zhang, HB; Li, Y; Sun, HD.Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera,ORGANIC LETTERS,2010,12(6):1208-1211
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