Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera
He, F; Pu, JX; Huang, SX; Wang, YY; Xiao, WL; Li, LM; Liu, JP; Zhang, HB; Li, Y; Sun, HD; pujianxin@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
2010
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号12期号:6页码:1208-1211
摘要A new cytotoxic triterpenold, schinalactone A (1), together with two new biogenetically related compounds, schinalactones B (2) and C (3), has been isolated from the roots and stems of Schisandra sphenanthera. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 showed significant cytotoxicity against PANC-1 cell lines with IC50 values of 5.9 and 4.1 mu M, respectively, A plausible biosynthetic pathway of 1 was also postulated.
部门归属[He, Fei; Pu, Jian-Xin; Huang, Sheng-Xiong; Wang, Yuan-Yuan; Xiao, Wei-Lie; Li, Li-Mei; Liu, Jing-Ping; Zhang, Hai-Bo; Li, Yan; Sun, Han-Dong] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China; [He, Fei] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresourses Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
学科领域Chemistry, Organic
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收录类别sci
资助项目LMB
WOS记录号WOS:000275379100017
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被引频次:36[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/3882
专题中科院海洋生物资源可持续利用重点实验室
通讯作者pujianxin@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
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He, F,Pu, JX,Huang, SX,et al. Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera[J]. ORGANIC LETTERS,2010,12(6):1208-1211.
APA He, F.,Pu, JX.,Huang, SX.,Wang, YY.,Xiao, WL.,...&hdsun@mail.kib.ac.cn.(2010).Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera.ORGANIC LETTERS,12(6),1208-1211.
MLA He, F,et al."Schinalactone A, a New Cytotoxic Triterpenoid from Schisandra sphenanthera".ORGANIC LETTERS 12.6(2010):1208-1211.
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