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Steroids from the South China Sea Gorgonian Subergorgia suberosa
Qi, SH; Gao, CH; Qian, PY; Zhang, S;
AbstractFrom the South China sea gorgonian Subergorgia suberosa, two new steroids, (22E)-14 alpha-hydroxy-cholesta-1,4,22-trien-3-one (1) and 3-(1',2'-ethandiol)-cholest-3 beta,5 alpha,6 alpha,11 alpha-tetraol (2) were obtained, in addition to six known steroids. The structures of compounds I and 2 were determined by spectroscopic methods. Cytotoxicity of the six known steroids against human cancer cell lines A549, HONE1, and HeLa was evaluated by MTT methods, and their anti-larval activity was evaluated in settlement inhibition assays with laboratory-reared Balanus amphitrite and Bugular neritina larvae.
Department[Qi, Shu-Hua; Gao, Cheng-Hai; Zhang, Si] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresourses Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Qian, Pei-Yuan] Hong Kong Univ Sci & Technol, Dept Biol, CML, KLN, Hong Kong, Hong Kong, Peoples R China
KeywordSubergorgia Suberosa Steroid Cytotoxicity Anti-larval
Subject AreaChemistry, Medicinal ; Food Science & Technology
Indexed Bysci
Funding ProjectLMB
WOS IDWOS:000275022700006
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Document Type期刊论文
Recommended Citation
GB/T 7714
Qi, SH,Gao, CH,Qian, PY,et al. Steroids from the South China Sea Gorgonian Subergorgia suberosa[J]. NATURAL PRODUCT COMMUNICATIONS,2010,5(2):201-204.
APA Qi, SH,Gao, CH,Qian, PY,Zhang, S,& from the South China Sea Gorgonian Subergorgia suberosa.NATURAL PRODUCT COMMUNICATIONS,5(2),201-204.
MLA Qi, SH,et al."Steroids from the South China Sea Gorgonian Subergorgia suberosa".NATURAL PRODUCT COMMUNICATIONS 5.2(2010):201-204.
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