A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species
Huang, RM; Ma, W; Dong, JD; Zhou, XF; Xu, TH; Lee, KJ; Yang, XW; Xu, SH; Liu, YH; huang_riming@hotmail.com; txush@jnu.edu.cn; yonghongliu@scsio.ac.cn
2010
发表期刊MOLECULES
ISSN1420-3049
卷号15期号:2页码:871-877
摘要A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), and cyclo-(S-Pro-R-Tyr) (5). The new structure was determined on the basis of NMR and MS analysis, and the absolute stereochemistry was defined by NOESY spectroscopy and optical rotation. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Callysponine (1) did not inhibit the growth of HepG2 (hepatoma carcinoma cell), A549 (lung carcinoma cell), and HeLa (cervical cancer cell) cell lines.
部门归属[Huang, Ri-Ming; Dong, Jun-De; Zhou, Xue-Feng; Yang, Xianwen; Liu, Yonghong] Jinan Univ, Dept Chem, Guangzhou 510632, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Peoples R China; [Ma, Wei] Guangzhou First Municipal Peoples Hosp, Guangzhou 510180, Peoples R China; [Huang, Ri-Ming] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; [Dong, Jun-De] Natl Expt Stn Trop Marine Biol, Sanya 572000, Peoples R China; [Xu, Tunhai] Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 100102, Peoples R China; [Lee, Kyung Jin] Natl Inst Biol Resources, Invertebrate Res Div, Inchon 404170, South Korea
关键词Marine Sponge CallySp.ngia Sp. Diazepine Callysponine
学科领域Chemistry, Organic
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收录类别sci
资助项目LMB
WOS记录号WOS:000274929200024
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被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/3896
专题中科院海洋生物资源可持续利用重点实验室
通讯作者huang_riming@hotmail.com; txush@jnu.edu.cn; yonghongliu@scsio.ac.cn
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Huang, RM,Ma, W,Dong, JD,et al. A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species[J]. MOLECULES,2010,15(2):871-877.
APA Huang, RM.,Ma, W.,Dong, JD.,Zhou, XF.,Xu, TH.,...&yonghongliu@scsio.ac.cn.(2010).A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species.MOLECULES,15(2),871-877.
MLA Huang, RM,et al."A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species".MOLECULES 15.2(2010):871-877.
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