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Three New Acylated Glycosides from the Stems of Casearia velutina and their Protective Effect Against H2O2-Induced Impairment in PC12 Cells
Chai, XY; Li, FF; Bai, CC; Xu, ZR; Shi, HM; Tu, PF; pengfeitu@vip.163.com
2010
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume76Issue:1Pages:91-93
AbstractChemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluated for protective effects against H2O2-induced impairment in PC12 cells and inhibitory activity against snake venom phosphodiesterase I. A brief chemotaxonomy of the genus Casearia is also discussed.
Department[Chai, Xing-Yun; Li, Fei-Fei; Bai, Chang-Cai; Xu, Zheng-Ren; Shi, Hai-Ming; Tu, Peng-Fei] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China; [Chai, Xing-Yun] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou, Guangdong, Peoples R China
KeywordCasearia Velutina Blume Salicaceae Casearicosides a - c Flacourtiaceae Chemotaxonomy
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
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Indexed Bysci
Funding ProjectLMB
WOS IDWOS:000273762100015
Citation statistics
Cited Times:9[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/3908
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorpengfeitu@vip.163.com
Recommended Citation
GB/T 7714
Chai, XY,Li, FF,Bai, CC,et al. Three New Acylated Glycosides from the Stems of Casearia velutina and their Protective Effect Against H2O2-Induced Impairment in PC12 Cells[J]. PLANTA MEDICA,2010,76(1):91-93.
APA Chai, XY.,Li, FF.,Bai, CC.,Xu, ZR.,Shi, HM.,...&pengfeitu@vip.163.com.(2010).Three New Acylated Glycosides from the Stems of Casearia velutina and their Protective Effect Against H2O2-Induced Impairment in PC12 Cells.PLANTA MEDICA,76(1),91-93.
MLA Chai, XY,et al."Three New Acylated Glycosides from the Stems of Casearia velutina and their Protective Effect Against H2O2-Induced Impairment in PC12 Cells".PLANTA MEDICA 76.1(2010):91-93.
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