中国科学院南海海洋研究所机构知识库
Advanced  
SCSIO OpenIR  > 中科院海洋生物资源可持续利用重点实验室  > 期刊论文
学科主题: Biochemistry & Molecular Biology; Zoology
题名: Interferon regulatory factor-2 in orange-spotted grouper (Epinephelus coioides): Gene, inductive expression pattern and subcellular localization
作者: Shi, Y ; Zhao, Z ; Yin, JK ; Zhu, XP ; Chen, KC ; Pan, DB ; Gui, JF
通讯作者: zhuxinping_1964@yahoo.com.cn
关键词: Interferon regulator factor-2 (IRF-2) ; Epinephelus coioides ; Genomic structure ; Inductive expression ; Subcellular localization
刊名: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
发表日期: 2010
卷: 155, 期:2, 页:110-117
收录类别: sci
部门归属: [Shi, Yan; Yin, Jing-Kui; Zhu, Xin-Ping; Chen, Kun-Ci; Pan, De-Bo] Chinese Acad Fishery Sci, Pearl River Fishery Res Inst, Guangzhou 510380, Guangdong, Peoples R China; [Zhao, Zhe] Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; [Zhu, Xin-Ping] Guangzhou Univ, Coll Life Sci, Guangzhou 510006, Guangdong, Peoples R China; [Gui, Jian-Fang] Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China
项目归属: LMB
摘要: Interferon regulatory factor 2 (IRF-2) is a multifunctional transcription factor which exhibits both transcriptional activating and repressing activities in the IRF family. In this study, we report an IRF-2 gene isolated from orange-spotted grouper (Epinephelus coioides). The 1854 bp full-length cDNA sequence of EcIRF-2 has been cloned, encoding a putative peptide of 336 amino acids which is highly consistent with the feature of IRF family members. The genomic fragment of EcIRF-2 contains nine exons and eight introns, spanning over approximate 8.8 kb. The expression of EcIRF-2 gene was detected in various tissues of healthy orange-spotted grouper and in four tissues after being challenged with poly I:C or LPS. EcIRF-2 gene is ubiquitously expressed in various healthy fish tissues and is up-regulated in vivo in response to poly I:C or LPS. Subcellular localization analysis of EcIRF-2 suggests it is an intranuclear protein in the fish cells. We believe this research is the first report of fish IRF-2 protein localization. The results in this research establish the base for further study of function mechanism of IRF family members in orange-spotted grouper. (C) 2009 Elsevier Inc. All rights reserved.
原文出处: 查看原文
WOS记录号: WOS:000273927000003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/3912
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Interferon regulatory factor-2 in orange-spotted grouper (Epinephelus coioides) Gene, inductive expression pattern and subcellular localization .pdf(1737KB)----开放获取--View Download

Recommended Citation:
Shi, Y; Zhao, Z; Yin, JK; Zhu, XP; Chen, KC; Pan, DB; Gui, JF.Interferon regulatory factor-2 in orange-spotted grouper (Epinephelus coioides): Gene, inductive expression pattern and subcellular localization,COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY,2010,155(2):110-117
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Shi, Y]'s Articles
[Zhao, Z]'s Articles
[Yin, JK]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Shi, Y]‘s Articles
[Zhao, Z]‘s Articles
[Yin, JK]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Interferon regulatory factor-2 in orange-spotted grouper (Epinephelus coioides) Gene, inductive expression pattern and subcellular localization .pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  中国科学院南海海洋研究所 - Feedback
Powered by CSpace