SCSIO OpenIR  > 中科院边缘海地质重点实验室
Relationship between structures of substituted indolic compounds and their degradation by marine anaerobic microorganisms
Gu, JD; Fan, YZ; Shi, HC
2002
发表期刊MARINE POLLUTION BULLETIN
ISSN0025-326X
卷号45期号:40555页码:379-384
摘要Degradation of selected indolic compounds including indole, 1-methylindole, 2-methylindole, and 3-methylindole was assessed under methanogenic and sulfate-reducing conditions using the serum-bottle anaerobic technique and marine sediment from Victoria Harbour, Hong Kong as an inoculum. Our results showed that indole degradation was achieved in 28 days by a methanogenic consortium and 35 days by a sulfate-reducing consortium. During degradation under both conditions, two intermediates were isolated, purified and identified as oxindole and isatin (indole-2,3-dione) suggesting that both methanogenic and sulfate-reducing bacteria use an identical degradation pathway. Degradation processes followed two steps of oxidation accomplished by hydroxylation and then dehydrogenation at 2- and then 3-position sequentially prior to the cleavage of the pyrrole ring between 2- and 3-positions. However, none of 1-methylindole or 2-methylindole was degraded under any conditions. 3-Methylindole (3-methyl-1H-indole, skatole) was transformed under methanogenic conditions and mineralized only under sulfate-reducing conditions. It is clear that methyl substitution on 1- or 2-position inhibits the initial attack by hydroxylation enzymes making them more persistent in the environment and posing longer toxic impact. (C) 2002 Elsevier Science Ltd. All rights reserved.
部门归属Univ Hong Kong, Dept Ecol & Biodivers, Lab Environm Toxicol, Hong Kong, Hong Kong, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanog, Guangzhou 510301, Peoples R China; Univ Hong Kong, Swire Inst Marine Sci, Shek O, Hong Kong, Peoples R China; Tsing Hua Univ, State Key Joint Lab Environm Simulat & Pollut Con, ESPC, Dept Environm Engn, Beijing 100084, Peoples R China
关键词Anaerobic Degradation Indole Metabolic Pathway Methanogenic Condition Substitution Sulfate-reducing Condition
学科领域Environmental Sciences ; Marine & Freshwater Biology
URL查看原文
收录类别sci
资助项目海洋地质
WOS记录号WOS:000178336300049
引用统计
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/4708
专题中科院边缘海地质重点实验室
推荐引用方式
GB/T 7714
Gu, JD,Fan, YZ,Shi, HC. Relationship between structures of substituted indolic compounds and their degradation by marine anaerobic microorganisms[J]. MARINE POLLUTION BULLETIN,2002,45(40555):379-384.
APA Gu, JD,Fan, YZ,&Shi, HC.(2002).Relationship between structures of substituted indolic compounds and their degradation by marine anaerobic microorganisms.MARINE POLLUTION BULLETIN,45(40555),379-384.
MLA Gu, JD,et al."Relationship between structures of substituted indolic compounds and their degradation by marine anaerobic microorganisms".MARINE POLLUTION BULLETIN 45.40555(2002):379-384.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Relationship between(172KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。