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学科主题: Chemistry, Applied; Chemistry, Medicinal
题名: In vitro antitumor activity of triterpenes from Ceriops tagal
作者: He, L ; Wang, YS ; Wang, QJ
通讯作者: yswang@scsio.ac.cn
关键词: Ceriops tagal ; rhizophoraceae ; antitumor ; triterpenes
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2007
卷: 21, 期:14, 页:1228-1233
收录类别: sci
部门归属: [He, Lei; Wang, You-Shao; Wang, Qing-Ji] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
项目归属: LMB
摘要: The embryo of Ceriops tagal was extracted with 95% ethanol at room temperature, and four triterpenes (1-4) were separated from this extract. For the first time these triterpenes were the separated from this plant. Compounds (1-4) were tested in vitro for antitumor activity against three cell lines (human liver cancer cell (H-7402), human B-lymphoblastoid cell (Raji). and human cervical carcinoma cell (Hela)). Compounds I and 3 were effective to inhibit cell proliferation and growth of H-7402 and Hela. the IC50 of them on H-7402 were 14.42 mu g mL(-1) and 9.97 mu g mL(-1). and the IC50 of them on Hela were 11.84 mu g mL(-1) and 11.32 mu g mL(-1) All compounds 1-4 were not effective to inhibit cell proliferation and growth of Raji. The effects of compound 4 on inhibiting proliferation and growth of these three cancer cells was also not obvious.
原文出处: 查看原文
WOS记录号: WOS:000252185200002
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/4902
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Recommended Citation:
He, L; Wang, YS; Wang, QJ.In vitro antitumor activity of triterpenes from Ceriops tagal,NATURAL PRODUCT RESEARCH,2007,21(14):1228-1233
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