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学科主题: Biotechnology & Applied Microbiology
题名: Inhibition of Vibrio biofilm formation by a marine actinomycete strain A66
作者: You, JL ; Xue, XL ; Cao, LX ; Lu, X ; Wang, J ; Zhang, LX ; Zhou, SN
通讯作者: zhanglixin@im.ac.cn ; lsszsl@zsu.edu.cn
关键词: Vibrio biofilm ; quorum sensing ; biocontrol
刊名: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
发表日期: 2007
卷: 76, 期:5, 页:1137-1144
收录类别: sci
部门归属: Sun Yat Sen Univ, Coll Life Sci, State Key Lab Biocontrol, Guangzhou 510275, Peoples R China; Chinese Acad Sci, Inst Microbiol, Beijing 100080, Peoples R China; Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510663, Peoples R China; Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Peoples R China; SynerZ Pharm, Lexington, MA USA
项目归属: LMB
摘要: China remains by far the largest aquaculture producer in the world. However, biofilms formed by pathogenic Vibrio strains pose serious problems to marine aquaculture. To provide a strategy for biofilm prevention, control, and eradication, extracts from 88 marine actinomycetes were screened. Thirty-five inhibited the biofilm formation of Vibrio harveyi, Vibrio vulnificus, and Vibrio anguillarum at a concentration of 2.5% (v/v). Thirty-three of the actinomycete extracts dispersed the mature biofilm. Six extracts inhibited the quorum-sensing system of V. harveyi by attenuating the signal molecules N-acylated homoserine lactones' activity. Strain A66, which was identified as Steptomyces albus, both attenuated the biofilms and inhibited their quorum-sensing system. It is suggested that strain A66 is a promising candidate to be used in future marine aquaculture.
原文出处: 查看原文
WOS记录号: WOS:000249522500020
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/4918
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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You, JL; Xue, XL; Cao, LX; Lu, X; Wang, J; Zhang, LX; Zhou, SN.Inhibition of Vibrio biofilm formation by a marine actinomycete strain A66,APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2007,76(5):1137-1144
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