Dimeric Proanthocyanidins from the Roots of Ephedra sinica
Tao, HM; Wang, LS; Cui, ZC; Zhao, DQ; Liu, YH; yonghongliu@scsio.ac.cn
2008
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号74期号:15页码:1823-1825
摘要Two new dimeric proanthocyanidins, ephedrannin B (2) and mahuannin E (4), along with two known congeners, ephedrannin A (1) and mahuannin D (3), were isolated from the roots of Ephedra sinica Stapf. Based on NMR, MS, and CD analysis, the structures of the new Compounds were deduced to be 5,7,4'-trihydroxyflavan-[4(alpha)-> 8,2(alpha)-> O -> 7]-kaempferol (2) and 5,7,4'-trihydroxyflavan-[4(beta)-> 8,2(beta)-> O -> 7]-epi-afzelechin (4). The compounds 1-4 were evaluated for cytotoxicity against three tumor cell lines (SGC-7901, HepG2, and HeLa), and 2 was found to be significantly active.
部门归属[Tao, Huaming; Liu, Yonghong] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China; [Tao, Huaming; Cui, Zhanchen] Jilin Univ, Coll Chem, Changchun 130023, Peoples R China; [Wang, Lishu; Zhao, Daqing] Changchun Univ Chinese Med, Coll Pharm, Changchun, Peoples R China; [Wang, Lishu] Jilin Prov Acad Chinese Med Sci, Changchun, Peoples R China
关键词Ephedra Sinica Stapf Ephedraceae Proanthocyanidins Ephedrannin b Mahuannin e Cytotoxicity
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
URL查看原文
收录类别sci
资助项目LMB
WOS记录号WOS:000262107800012
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被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/4936
专题中科院海洋生物资源可持续利用重点实验室
通讯作者yonghongliu@scsio.ac.cn
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GB/T 7714
Tao, HM,Wang, LS,Cui, ZC,et al. Dimeric Proanthocyanidins from the Roots of Ephedra sinica[J]. PLANTA MEDICA,2008,74(15):1823-1825.
APA Tao, HM,Wang, LS,Cui, ZC,Zhao, DQ,Liu, YH,&yonghongliu@scsio.ac.cn.(2008).Dimeric Proanthocyanidins from the Roots of Ephedra sinica.PLANTA MEDICA,74(15),1823-1825.
MLA Tao, HM,et al."Dimeric Proanthocyanidins from the Roots of Ephedra sinica".PLANTA MEDICA 74.15(2008):1823-1825.
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