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Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis
Qi, SH; Zhang, S; Yang, LH; Qian, PY; boqianpy@ust.hk
2008
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
Volume22Issue:2Pages:154-166
AbstractIn this study, we investigated the potential antilarval and antibacterial activity of secondary metabolites of the gorgonians Subergorgia suberosa and Scripearia gracillis from the South China Sea. Fresh specimens of these two gorgonian corals were collected from a shallow reef in Sanya Bay of Hainan Island and extracted with different solvents. Antilarval activity of the chemical extracts and pure compounds was evaluated in settlement inhibition assays with laboratory-reared Balanus amphitrite and Bugula neritina larvae, while antibacterial activity was assessed with disc diffusion bioassay on growth inhibition of 15 marine bacterial species. Using bioassay-guided procedures, we purified and identified nine compounds. The most potent metabolites produced by these gorgonian corals were subergorgic acid and pregn-4-ene-3, 20-dione extracted from S. suberosa. Our results show that the gorgonian coral S. suberosa and S. gracillis can produce potent anti-fouling compounds that deserve further exploration.
Department[Qi, S. H.; Qian, P. Y.] Hong Kong Univ Sci & Technol, Dept Biol, KLN, Hong Kong, Hong Kong, Peoples R China; [Qi, S. H.; Qian, P. Y.] Hong Kong Univ Sci & Technol, Coastal Marine Lab, KLN, Hong Kong, Hong Kong, Peoples R China; [Qi, S. H.; Zhang, S.] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Materia Med, Guangzhou 510301, Guangdong, Peoples R China
KeywordSubergorgia Suberosa Scripearia Gracillis Anti-fouling Antibacterial Secondary Metabolites
Subject AreaChemistry, Applied ; Chemistry, Medicinal
Indexed Bysci
Funding ProjectLMB
WOS IDWOS:000252342300008
Citation statistics
Cited Times:68[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.scsio.ac.cn/handle/344004/5018
Collection中科院海洋生物资源可持续利用重点实验室
Corresponding Authorboqianpy@ust.hk
Recommended Citation
GB/T 7714
Qi, SH,Zhang, S,Yang, LH,et al. Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis[J]. NATURAL PRODUCT RESEARCH,2008,22(2):154-166.
APA Qi, SH,Zhang, S,Yang, LH,Qian, PY,&boqianpy@ust.hk.(2008).Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis.NATURAL PRODUCT RESEARCH,22(2),154-166.
MLA Qi, SH,et al."Antifouling and antibacterial compounds from the gorgonians Subergorgia suberosa and Scripearia gracillis".NATURAL PRODUCT RESEARCH 22.2(2008):154-166.
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