A novel rearrangement in the mitochondrial genome of tongue sole, Cynoglossus semilaevis: control region translocation and a tRNA gene inversion
Kong, XY; Dong, XL; Zhang, YC; Shi, W; Wang, ZM; Yu, ZN; xykong@scsio.ac.cn
2009
发表期刊GENOME
ISSN0831-2796
卷号52期号:12页码:975-984
摘要The organization of fish mitochondrial genomes (mitogenomes) is quite conserved, usually with the heavy strand encoding 12 of 13 protein-coding genes and 14 of 22 tRNA genes, and the light strand encoding ND6 and the remaining 8 tRNA genes. Currently, there arc only a few reports on gene reorganization of fish mitogenomes, with only two types of rearrangements (shuffling and translocation) observed. No gene inversion has been detected in approximately 420 complete fish mitogenomes available so far. Here we report a novel rearrangement in the mitogenome of Cynoglossus semilaevis (Cynoglossinae, Cynoglossidae, Pleuronectiformes). The genome is 16371 bp in length and contains 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 2 main noncoding regions, the putative control region and the light-strand replication origin. A striking finding of this study is that the tRNA(Gln) gene is translocated from the light to the heavy strand (Q inversion). This is accompanied by shuffling of the tRNA(Ile) gene and long-range translocation of the putative control region downstream to a site between NDI and the tRNA(Gln) gene. The remaining gene order is identical to that of typical Fish mitogenomes. Additionally, unique characters of this mitogenome, including a high A+T content and length variations of 8 protein-coding genes, were found through comparison of the mitogenome sequence with those from other flatfishes. All the features detected and their relationships with the rearrangements, as well as a possible rearrangement pathway, are discussed. These data provide interesting information for better understanding the molecular mechanisms of gene reorganization in fish mitogenomes.
部门归属[Kong, Xiaoyu; Wang, Zhongming; Yu, Ziniu] Chinese Acad Sci, S China Sea Inst Oceanol, Lab Marine Bioresource Sustainable Utilizat, Guangzhou, Guangdong, Peoples R China; [Dong, Xiaoli; Zhang, Yanchun; Shi, Wei] Ocean Univ China, Coll Fisheries, Lab Mariculture Res, Qingdao, Peoples R China
关键词Cynoglossus Semilaevis Mitogenome Sequence Trna Gene Inversion Translocation Of Control Region Gene Reorganization Flatfish
学科领域Biotechnology & Applied Microbiology ; Genetics & Heredity
URL查看原文
收录类别sci
资助项目LMB
WOS记录号WOS:000273721400001
引用统计
被引频次:37[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.scsio.ac.cn/handle/344004/5028
专题中科院海洋生物资源可持续利用重点实验室
通讯作者xykong@scsio.ac.cn
推荐引用方式
GB/T 7714
Kong, XY,Dong, XL,Zhang, YC,et al. A novel rearrangement in the mitochondrial genome of tongue sole, Cynoglossus semilaevis: control region translocation and a tRNA gene inversion[J]. GENOME,2009,52(12):975-984.
APA Kong, XY.,Dong, XL.,Zhang, YC.,Shi, W.,Wang, ZM.,...&xykong@scsio.ac.cn.(2009).A novel rearrangement in the mitochondrial genome of tongue sole, Cynoglossus semilaevis: control region translocation and a tRNA gene inversion.GENOME,52(12),975-984.
MLA Kong, XY,et al."A novel rearrangement in the mitochondrial genome of tongue sole, Cynoglossus semilaevis: control region translocation and a tRNA gene inversion".GENOME 52.12(2009):975-984.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
A novel rearrangemen(751KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。