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学科主题: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
题名: Chemical Constituents of Dracocephalum forrestii
作者: Li, SM ; Yang, XW ; Li, YL ; Shen, YH ; Feng, L ; Wang, YH ; Zeng, HW ; Liu, XH ; Zhang, CS ; Long, CL ; Zhang, WD
通讯作者: long@mail.kib.ac.cn ; wdzhangy@hotmail.com
关键词: Dracocephalum forrestii ; Lamiaceae ; phenylethanoids ; lignans ; RAW 264.7 macrophages ; NO
刊名: PLANTA MEDICA
发表日期: 2009
卷: 75, 期:15, 页:1591-1596
收录类别: sci
部门归属: [Li, Su-Mei; Wang, Yue-Hu; Long, Chun-Lin] Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China; [Yang, Xian-Wen; Li, Yong-Li; Shen, Yun-Heng; Feng, Lin; Zeng, Hua-Wu; Liu, Xiao-Hua; Zhang, Wei-Dong] Mil Med Coll 2, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China; [Li, Su-Mei; Yang, Xian-Wen; Zhang, Chang-Sheng] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
项目归属: LMB
摘要: A systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8-O-[(6-O-syringoyl)-beta-D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta-D-glucopyranoside (2), 4-O-[beta-D-glucopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9 ''-O-n-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations.
原文出处: 查看原文
WOS记录号: WOS:000273178400007
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内容类型: 期刊论文
URI标识: http://ir.scsio.ac.cn/handle/344004/5032
Appears in Collections:中科院海洋生物资源可持续利用重点实验室_期刊论文

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Li, SM; Yang, XW; Li, YL; Shen, YH; Feng, L; Wang, YH; Zeng, HW; Liu, XH; Zhang, CS; Long, CL; Zhang, WD.Chemical Constituents of Dracocephalum forrestii,PLANTA MEDICA,2009,75(15):1591-1596
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